Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 1/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.37 |
| ▸ | LMNA | P02545 | 2/20 | 0.36 |
| ▸ | HTT | P42858 | 2/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | NMT1 | P30419 | 5/20 | 0.35 |
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.33 |
| ▸ | TLR8 | Q9NR97 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6495036 | 0.74 | GAA (0.46) | GAAKDM4EALDH1A1LMNAHTT | |
| SCHEMBL10864189 | 0.69 | RAB9A (0.43) | GAAKDM4EALDH1A1LMNASMN1; SMN2 | |
| SCHEMBL11665814 | 0.68 | GAA (0.49) | GAAKDM4EALDH1A1LMNAHTT | |
| SCHEMBL10942236 | 0.68 | ALDH1A1 (0.42) | GAAKDM4EALDH1A1LMNAHTT | |
| SCHEMBL10939649 | 0.67 | ALDH1A1 (0.41) | GAAKDM4EALDH1A1HTT | |
| SCHEMBL10934120 | 0.67 | SMN1; SMN2 (0.43) | GAAKDM4EALDH1A1LMNAHTT | |
| SCHEMBL11755254 | 0.66 | KAT2B (0.46) | ALDH1A1HTTHSD17B10 | |
| SCHEMBL10933806 | 0.65 | HPGD (0.44) | ALDH1A1TSHRTLR8 | |
| SCHEMBL10838540 | 0.65 | SMN1; SMN2 (0.56) | KDM4EALDH1A1LMNAHTTSMN1; SMN2 | |
| SCHEMBL6917528 | 0.65 | GAA (0.48) | GAAKDM4EALDH1A1LMNAHTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4507488-A | N-Pyrazolylalkylenediamine intermediates | BOEHRINGER MANNHEIM GMBH (DE) | 1985-03-26 | — | — | US | disclosed |
| EP-0042592-B1 | N-HETEROARYLALKYLENE DIAMINES, PROCESS FOR THEIR PREPARATION AND THEIR USE | Roche Diagnostics GmbH (DE) | 1985-01-30 | — | — | EP | disclosed |