SCHEMBL10936288

SCHEMBL10936288

C=C(C)C(=O)OCCOC(=O)c1cc(S(=O)(=O)c2ccccc2)cc2sc3ccccc3c(=O)c12

nearest known ligand 0.38

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MAOA P21397 10/20 0.38
MAOB P27338 10/20 0.38
MAPT P10636 3/20 0.36
ALDH1A1 P00352 2/20 0.36
MEN1 O00255 1/20 0.36
POLB P06746 1/20 0.36
GAA P10253 1/20 0.36
KMT2A Q03164 1/20 0.36
HSD11B1 P28845 1/20 0.32
NPC1 O15118 2/20 0.32
RAB9A P51151 2/20 0.32
CYP1A2 P05177 1/20 0.32
CYP3A4 P08684 1/20 0.32
CYP2C9 P11712 1/20 0.32
HPGD P15428 1/20 0.32
CYP2C19 P33261 1/20 0.32
NAMPT P43490 1/20 0.32
DHODH Q02127 1/20 0.32
GABRP O00591 1/20 0.31
GABRD O14764 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10940641 0.86 MAOA (0.42) MAOAMAOBMAPTALDH1A1MEN1
SCHEMBL51954 0.85 GABRP (0.44) MAOAMAOBMAPTALDH1A1MEN1
SCHEMBL30119823 0.85 GABRP (0.44) MAOAMAOBMAPTALDH1A1MEN1
SCHEMBL10843289 0.82 MAPT (0.40) MAOAMAOBMAPTALDH1A1MEN1
SCHEMBL29052637 0.80 GABRP (0.40) MAOAMAOBMAPTALDH1A1MEN1
SCHEMBL4431580 0.78 MAOA (0.41) MAOAMAOBMAPTALDH1A1MEN1
SCHEMBL29236397 0.76 PKM (0.36) MAOAMAOBMAPTALDH1A1MEN1
SCHEMBL11169681 0.75 GABRP (0.46) MAOAMAOBMAPTALDH1A1MEN1
SCHEMBL10841616 0.75 MAPT (0.37) MAOAMAOBMAPTALDH1A1MEN1
SCHEMBL12284025 0.74 ALDH1A1 (0.45) MAOAMAOBMAPTALDH1A1MEN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-4560643-A BLEND OF AROMATIC KETONE, POLYMER, AND GROUP IB OR EIGHT METAL SALT CIBA GEIGY CORPORATION (US) 1985-12-24 US disclosed