Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM6B | O15054 | 7/20 | 0.51 |
| ▸ | KDM4C | Q9H3R0 | 7/20 | 0.51 |
| ▸ | KDM4D | Q6B0I6 | 4/20 | 0.51 |
| ▸ | EGLN3 | Q9H6Z9 | 1/20 | 0.51 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.45 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.45 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.45 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.45 |
| ▸ | LMNA | P02545 | 1/20 | 0.44 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.44 |
| ▸ | TBXAS1 | P24557 | 2/20 | 0.43 |
| ▸ | CYP1A1 | P04798 | 1/20 | 0.43 |
| ▸ | CYP1B1 | Q16678 | 1/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.43 |
| ▸ | KDM4A | O75164 | 1/20 | 0.43 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.42 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.42 |
| ▸ | FAAH | O00519 | 1/20 | 0.40 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11397439 | 0.83 | KEAP1 (0.52) | FFAR1CYP1A1CYP1B1KEAP1TDP1 | |
| SCHEMBL7194181 | 0.75 | KDM4C (0.41) | KDM6BKDM4CKDM4DCYP1A2CYP3A4 | |
| SCHEMBL4581478 | 0.74 | KMT2A (0.52) | KDM6BKDM4CKDM4DCYP1A2CYP3A4 | |
| SCHEMBL1660949 | 0.73 | CYP19A1 (0.69) | CYP1A2CYP3A4CYP2C9CYP2C19LMNA | |
| SCHEMBL11304333 | 0.72 | TDP1 (0.62) | CYP1A2CYP3A4CYP2C9CYP2C19LMNA | |
| SCHEMBL3247901 | 0.71 | PLOD2 (0.65) | CYP1A2CYP3A4CYP2C9CYP2C19LMNA | |
| SCHEMBL30965433 | 0.71 | PLOD2 (0.65) | CYP1A2CYP3A4CYP2C9CYP2C19LMNA | |
| SCHEMBL14141727 | 0.70 | CYP19A1 (0.42) | CYP1A2CYP3A4CYP2C9CYP2C19LMNA | |
| SCHEMBL5610674 | 0.70 | TDP1 (0.52) | KDM6BKDM4CKDM4DKDM4EKDM4A | |
| SCHEMBL5610323 | 0.70 | KDM4C (0.41) | KDM6BKDM4CKDM4DCYP3A4CYP2C9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0148883-A1 | ALLOPURINOL PRODRUGS. | GEA AS (DK) | 1985-07-24 | — | — | EP | disclosed |
| WO-1985000368-A1 | ALLOPURINOL PRODRUGS | A/S GEA (DK) | 1985-01-31 | — | — | WO | disclosed |