Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EPHX1 | P07099 | 2/20 | 0.48 |
| ▸ | TP53 | P04637 | 1/20 | 0.48 |
| ▸ | TSHR | P16473 | 1/20 | 0.48 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.48 |
| ▸ | CDK9 | P50750 | 1/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.48 |
| ▸ | CLK4 | Q9HAZ1 | 1/20 | 0.48 |
| ▸ | MEN1 | O00255 | 2/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.47 |
| ▸ | NPC1 | O15118 | 1/20 | 0.47 |
| ▸ | RAB9A | P51151 | 1/20 | 0.47 |
| ▸ | TGM2 | P21980 | 1/20 | 0.46 |
| ▸ | HPGD | P15428 | 2/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.45 |
| ▸ | LMNA | P02545 | 1/20 | 0.45 |
| ▸ | MAPT | P10636 | 2/20 | 0.43 |
| ▸ | CASP3 | P42574 | 1/20 | 0.43 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.43 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.43 |
| ▸ | POLB | P06746 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11147820 | 0.88 | TGM2 (0.46) | EPHX1TP53TSHREPHX2CDK9 | |
| SCHEMBL10943175 | 0.86 | MAOA (0.45) | EPHX1TP53TSHRMEN1KMT2A | |
| SCHEMBL8558364 | 0.85 | CYP1A2 (0.46) | MEN1KMT2ATGM2HPGDALDH1A1 | |
| SCHEMBL10856338 | 0.85 | CDK2 (0.52) | TP53TSHRMEN1KMT2ANPC1 | |
| SCHEMBL11177161 | 0.85 | CNR1 (0.47) | EPHX1TSHREPHX2SMN1; SMN2MEN1 | |
| SCHEMBL10857357 | 0.85 | SMN1; SMN2 (0.53) | SMN1; SMN2MEN1KMT2ARAB9ALMNA | |
| SCHEMBL1649522 | 0.83 | EPHX1 (0.59) | EPHX1TP53TSHREPHX2CDK9 | |
| Ammonia Solution, Strong SCHEMBL11319855 | 0.82 | EPHX1 (0.57) | EPHX1TP53TSHREPHX2CDK9 | |
| SCHEMBL10852703 | 0.80 | RAB9A (0.51) | SMN1; SMN2MEN1KMT2ANPC1RAB9A | |
| SCHEMBL1074279 | 0.79 | LMNA (0.62) | TP53SMN1; SMN2MEN1KMT2ANPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4564640-A | Amidinoureas substituted in both the urea and amidino nitrogen positions | WILLIAM H. RORER, INC. (US) | 1986-01-14 | — | — | US | disclosed |
| US-4418209-A | ANTIULCER, ANTIARRYTHMIC, ANTIDIARRHEAL, ANTISPASMODIC, ANTIPARASITIC, AND ANTISECRETORY AGENTS | WILLIAM H. RORER, INC. (US) | 1983-11-29 | — | — | US | disclosed |