SCHEMBL109395

SCHEMBL109395

CCCOC(=O)CCSCCC(=O)OCCC

nearest known ligand 0.57

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
DGKA P23743 1/20 0.48
ALDH1A1 P00352 6/20 0.42
HPGD P15428 1/20 0.42
ADRA2A P08913 1/20 0.41
ADRA1A P35348 1/20 0.41
MAPT P10636 2/20 0.40
DNM1 Q05193 1/20 0.40
PLA2G4B P0C869 1/20 0.40
BLM P54132 1/20 0.40
HTR2C P28335 1/20 0.39
NAAA Q02083 1/20 0.39
LMNA P02545 1/20 0.39
KMT2A Q03164 1/20 0.39
HSD17B10 Q99714 1/20 0.39
TDP1 Q9NUW8 1/20 0.39
HCAR2 Q8TDS4 1/20 0.38
MAPK1 P28482 1/20 0.37
GLA P06280 1/20 0.37
TOP2A P11388 1/20 0.36
TSHR P16473 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10666704 0.96 DGKA (0.45) DGKAALDH1A1HPGDADRA2AADRA1A
SCHEMBL5014579 0.92 LMNA (0.54) DGKAALDH1A1HPGDADRA2AADRA1A
SCHEMBL17371400 0.91 DGKA (0.45) DGKAALDH1A1HPGDADRA2AADRA1A
SCHEMBL6616344 0.90 DGKA (0.41) DGKAALDH1A1HPGDADRA2AADRA1A
SCHEMBL28707585 0.89 NAAA (0.58) DGKADNM1PLA2G4BHTR2CNAAA
SCHEMBL112324 0.87 DGKA (0.55) DGKAALDH1A1HPGDMAPTDNM1
SCHEMBL283830 0.86 DGKA (0.48) DGKAALDH1A1ADRA2AADRA1AMAPT
SCHEMBL29986668 0.85 NAAA (0.59) DGKADNM1PLA2G4BHTR2CNAAA
SCHEMBL15222131 0.84 DGKA (0.47) DGKAALDH1A1ADRA2AADRA1AMAPT
SCHEMBL16865882 0.84 DGKA (0.37) DGKAALDH1A1HPGDADRA2AADRA1A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 41 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-102802605-A Stable lipid formulations of apoptosis promoters ABBOTT LAB 2012-11-28 CN claimed
EP-2424499-A1 STABILIZED LIPID FORMULATION OF APOPTOSIS PROMOTER Abbott Laboratories (US) 2012-03-07 EP claimed
WO-2010127193-A1 STABILIZED LIPID FORMULATION OF APOPTOSIS PROMOTER ABBOTT LABORATORIES (US) 2010-11-04 WO claimed
US-20100278905-A1 STABILIZED LIPID FORMULATION OF APOPTOSIS PROMOTER ABBVIE INC. 2010-11-04 US claimed
CN-115521435-A Resin, curable resin composition, cured product, insulating material, and resist member DIC株式会社 2022-12-27 CN disclosed
US-20220326613-A1 PHOTOSENSITIVE TRANSFER MATERIAL AND METHOD OF PRODUCING THE SAME, METHOD OF PRODUCING PATTERNED METAL CONDUCTIVE MATERIAL, FILM, TOUCH PANEL, METHOD OF SUPPRESSING DETERIORATION, AND LAMINATE FUJIFILM CORPORATION (JP) 2022-10-13 US disclosed
WO-2020040249-A1 HEAT-RESISTANT RELEASE AGENT COMPOSITION 株式会社ネオス 2020-02-27 WO disclosed
US-9309481-B2 Lubricant composition IDEMITSU KOSAN CO., LTD. (JP) 2016-04-12 US disclosed
CN-102802605-B Stable lipid formulations of apoptosis promoters ABBVIE (US) 2015-08-12 CN disclosed
US-8927009-B2 ABT-263 capsule ABBVIE INC. (US) 2015-01-06 US disclosed
US-8728516-B2 Stabilized lipid formulation of apoptosis promoter ABBVIE INC. (US) 2014-05-20 US disclosed
US-8513243-B2 ABT-263 crystalline forms ABBVIE INC. (US) 2013-08-20 US disclosed
WO-2010127198-A1 FORMULATION FOR ORAL ADMINISTRATION OF APOPTOSIS PROMOTER ABBOTT LABORATORIES (US) 2010-11-04 WO disclosed
WO-2010127193-A1 STABILIZED LIPID FORMULATION OF APOPTOSIS PROMOTER ABBOTT LABORATORIES (US) 2010-11-04 WO disclosed
US-20100278905-A1 STABILIZED LIPID FORMULATION OF APOPTOSIS PROMOTER ABBVIE INC. 2010-11-04 US disclosed
EP-1947725-A2 Polymer electrolyte composition and fuel cell Sumitomo Chemical Company, Limited (JP) 2008-07-23 EP disclosed
EP-1289041-B1 Polymer electrolyte composition and fuel cell SUMITOMO CHEMICAL CO (JP) 2008-03-12 EP disclosed
US-20060257706-A1 POLYMER ELECTROLYTE COMPOSITION AND FUEL CELL HIDAKA YASUAKI 2006-11-16 US disclosed
US-20030113605-A1 Polymer electrolyte composition and fuel cell SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2003-06-19 US disclosed
EP-1289041-A2 Polymer electrolyte composition and fuel cell SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2003-03-05 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20100278905-A1 STABILIZED LIPID FORMULATION OF APOPTOSIS PROMOTER BCL2, BAX, BCOR DGKA 2084/4885ALDH1A1 3985/4885HPGD 806/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.