Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ENPP2 | Q13822 | 4/20 | 0.76 |
| ▸ | SUMO2 | P61956 | 1/20 | 0.68 |
| ▸ | SUMO1 | P63165 | 1/20 | 0.68 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.68 |
| ▸ | SENP2 | Q9HC62 | 1/20 | 0.68 |
| ▸ | APEX1 | P27695 | 2/20 | 0.61 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.47 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.47 |
| ▸ | PHLPP2 | Q6ZVD8 | 1/20 | 0.46 |
| ▸ | CDK1 | P06493 | 2/20 | 0.46 |
| ▸ | CDK2 | P24941 | 2/20 | 0.46 |
| ▸ | MEN1 | O00255 | 2/20 | 0.45 |
| ▸ | MAPT | P10636 | 2/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.45 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.45 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.45 |
| ▸ | NPC1 | O15118 | 1/20 | 0.45 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.45 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.45 |
| ▸ | RECQL | P46063 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10940519 | 1.00 | ENPP2 (0.76) | ENPP2SUMO2SUMO1SENP7SENP2 | |
| SCHEMBL11765850 | 0.91 | SUMO2 (0.81) | ENPP2SUMO2SUMO1SENP7SENP2 | |
| SCHEMBL11765859 | 0.91 | SUMO2 (0.81) | ENPP2SUMO2SUMO1SENP7SENP2 | |
| SCHEMBL11670234 | 0.89 | SUMO2 (0.74) | ENPP2SUMO2SUMO1SENP7SENP2 | |
| SCHEMBL11670202 | 0.87 | SUMO2 (0.72) | ENPP2SUMO2SUMO1SENP7SENP2 | |
| SCHEMBL10941472 | 0.87 | SUMO2 (0.72) | ENPP2SUMO2SUMO1SENP7SENP2 | |
| SCHEMBL10941468 | 0.87 | SUMO2 (0.72) | ENPP2SUMO2SUMO1SENP7SENP2 | |
| SCHEMBL14418348 | 0.87 | SUMO2 (0.72) | ENPP2SUMO2SUMO1SENP7SENP2 | |
| SCHEMBL26459720 | 0.87 | SUMO2 (0.72) | ENPP2SUMO2SUMO1SENP7SENP2 | |
| SCHEMBL3410648 | 0.85 | APEX1 (0.77) | ENPP2SUMO2SUMO1SENP7SENP2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0070972-B1 | UREYLENEBIS (HYDROXYNAPHTHALENESULFONIC ACIDS) | AMERICAN CYANAMID COMPANY (US) | 1985-12-11 | — | — | EP | disclosed |
| EP-0070972-A1 | Ureylenebis (hydroxynaphthalenesulfonic acids) | AMERICAN CYANAMID COMPANY (US) | 1983-02-09 | — | — | EP | disclosed |