Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SUMO2 | P61956 | 1/20 | 0.81 |
| ▸ | SUMO1 | P63165 | 1/20 | 0.81 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.81 |
| ▸ | SENP2 | Q9HC62 | 1/20 | 0.81 |
| ▸ | ENPP2 | Q13822 | 4/20 | 0.63 |
| ▸ | APEX1 | P27695 | 2/20 | 0.55 |
| ▸ | CYP2C9 | P11712 | 3/20 | 0.53 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.53 |
| ▸ | NT5E | P21589 | 2/20 | 0.51 |
| ▸ | PHLPP2 | Q6ZVD8 | 2/20 | 0.51 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.47 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.47 |
| ▸ | CASP6 | P55212 | 1/20 | 0.47 |
| ▸ | CDK1 | P06493 | 1/20 | 0.46 |
| ▸ | CDK2 | P24941 | 1/20 | 0.46 |
| ▸ | PRMT1 | Q99873 | 1/20 | 0.46 |
| ▸ | THRB | P10828 | 1/20 | 0.44 |
| ▸ | POLB | P06746 | 1/20 | 0.44 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11765859 | 1.00 | SUMO2 (0.81) | SUMO2SUMO1SENP7SENP2ENPP2 | |
| SCHEMBL11670234 | 0.95 | SUMO2 (0.74) | SUMO2SUMO1SENP7SENP2ENPP2 | |
| SCHEMBL11670202 | 0.94 | SUMO2 (0.72) | SUMO2SUMO1SENP7SENP2ENPP2 | |
| SCHEMBL10941468 | 0.94 | SUMO2 (0.72) | SUMO2SUMO1SENP7SENP2ENPP2 | |
| SCHEMBL26459720 | 0.94 | SUMO2 (0.72) | SUMO2SUMO1SENP7SENP2ENPP2 | |
| SCHEMBL10941472 | 0.94 | SUMO2 (0.72) | SUMO2SUMO1SENP7SENP2ENPP2 | |
| SCHEMBL14418348 | 0.94 | SUMO2 (0.72) | SUMO2SUMO1SENP7SENP2ENPP2 | |
| SCHEMBL7790539 | 0.91 | SENP2 (0.68) | SUMO2SUMO1SENP7SENP2ENPP2 | |
| SCHEMBL7790541 | 0.91 | SENP2 (0.68) | SUMO2SUMO1SENP7SENP2ENPP2 | |
| SCHEMBL10940519 | 0.91 | ENPP2 (0.76) | SUMO2SUMO1SENP7SENP2ENPP2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4008320-A | Amidophenyl-azo-naphthalenesulfonic complement inhibitors and method of use thereof | AMERICAN CYANAMID COMPANY (US) | 1977-02-15 | — | — | US | disclosed |