Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SUMO2 | P61956 | 2/20 | 0.72 |
| ▸ | SUMO1 | P63165 | 2/20 | 0.72 |
| ▸ | SENP7 | Q9BQF6 | 2/20 | 0.72 |
| ▸ | SENP2 | Q9HC62 | 2/20 | 0.72 |
| ▸ | ENPP2 | Q13822 | 5/20 | 0.68 |
| ▸ | APEX1 | P27695 | 2/20 | 0.51 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.50 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.50 |
| ▸ | NT5E | P21589 | 2/20 | 0.50 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.50 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.50 |
| ▸ | PHLPP2 | Q6ZVD8 | 3/20 | 0.48 |
| ▸ | PRMT1 | Q99873 | 1/20 | 0.45 |
| ▸ | MEN1 | O00255 | 1/20 | 0.45 |
| ▸ | HTT | P42858 | 1/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.45 |
| ▸ | CDK1 | P06493 | 1/20 | 0.43 |
| ▸ | CDK2 | P24941 | 1/20 | 0.43 |
| ▸ | SENP3 | Q9H4L4 | 1/20 | 0.43 |
| ▸ | SENP1 | Q9P0U3 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14418348 | 1.00 | SUMO2 (0.72) | SUMO2SUMO1SENP7SENP2ENPP2 | |
| SCHEMBL26459322 | 0.94 | SUMO2 (0.65) | SUMO2SUMO1SENP7SENP2ENPP2 | |
| SCHEMBL25511892 | 0.94 | SUMO2 (0.65) | SUMO2SUMO1SENP7SENP2ENPP2 | |
| SCHEMBL11765859 | 0.94 | SUMO2 (0.81) | SUMO2SUMO1SENP7SENP2ENPP2 | |
| SCHEMBL11765850 | 0.94 | SUMO2 (0.81) | SUMO2SUMO1SENP7SENP2ENPP2 | |
| SCHEMBL10941468 | 0.93 | SUMO2 (0.72) | SUMO2SUMO1SENP7SENP2ENPP2 | |
| SCHEMBL10941472 | 0.93 | SUMO2 (0.72) | SUMO2SUMO1SENP7SENP2ENPP2 | |
| SCHEMBL11670234 | 0.91 | SUMO2 (0.74) | SUMO2SUMO1SENP7SENP2ENPP2 | |
| SCHEMBL11670202 | 0.90 | SUMO2 (0.72) | SUMO2SUMO1SENP7SENP2ENPP2 | |
| SCHEMBL7790539 | 0.90 | SENP2 (0.68) | SUMO2SUMO1SENP7SENP2ENPP2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230127304-A1 | NEW INHIBITORS FOR THE KEAP1-NRF2 PROTEIN-PROTEIN INTERACTION | PRESIDENT AND FELLOWS OF HARVARD COLLEGE (US) | 2023-04-27 | — | — | US | disclosed |
| US-20230127304-A1 | NEW INHIBITORS FOR THE KEAP1-NRF2 PROTEIN-PROTEIN INTERACTION | PRESIDENT AND FELLOWS OF HARVARD COLLEGE (US) | 2023-04-27 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230127304-A1 | NEW INHIBITORS FOR THE KEAP1-NRF2 PROTEIN-PROTEIN INTERACTION | KEAP1, HMOX1, NFE2L2 | SUMO2 1521/4885SUMO1 1055/4885SENP7 3092/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.