Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 1/20 | 0.47 |
| ▸ | FDPS | P14324 | 3/20 | 0.45 |
| ▸ | PGK1 | P00558 | 1/20 | 0.36 |
| ▸ | PGK2 | P07205 | 1/20 | 0.36 |
| ▸ | CA2 | P00918 | 1/20 | 0.35 |
| ▸ | GRM4 | Q14833 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL97568 | 0.89 | LMNA (0.56) | LMNAFDPSPGK1PGK2CA2 | |
| Methyl Phosphonate SCHEMBL9146912 | 0.83 | CA2 (0.57) | LMNAFDPSPGK1PGK2CA2 | |
| SCHEMBL14029134 | 0.73 | LMNA (0.47) | LMNAFDPSPGK1PGK2CA2 | |
| Aminomethylenebisphosphonic Acid SCHEMBL11025149 | 0.71 | FDPS (0.43) | LMNAFDPSGRM4 | |
| SCHEMBL335957 | 0.70 | — | — | |
| Phosphoric Acid SCHEMBL28561793 | 0.67 | LMNA (0.56) | LMNAFDPSPGK1PGK2CA2 | |
| SCHEMBL4147247 | 0.67 | LMNA (0.56) | LMNAFDPSPGK1PGK2CA2 | |
| SCHEMBL4649888 | 0.67 | — | — | |
| Hydrochloric Acid SCHEMBL9775705 | 0.67 | LMNA (0.56) | LMNAFDPSPGK1PGK2CA2 | |
| SCHEMBL27006289 | 0.67 | LMNA (0.56) | LMNAFDPSPGK1PGK2CA2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0068584-B1 | BORON CONTAINING POLYPHOSPHONATES FOR THE TREATMENT OF CALCIFIC TUMORS | THE PROCTER & GAMBLE COMPANY (US) | 1985-09-25 | — | — | EP | disclosed |