SCHEMBL10940993

SCHEMBL10940993

CNC(=O)C[Si](C)(OC)OC

nearest known ligand 0.35

Predicted protein targets (top 5)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 1/20 0.35
MAPT P10636 1/20 0.35
MCL1 Q07820 1/20 0.34
LMNA P02545 1/20 0.34
TSHR P16473 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10946037 0.80 ALDH1A1 (0.38) ALDH1A1MAPTMCL1LMNATSHR
SCHEMBL915521 0.77 MCL1 (0.39) ALDH1A1MCL1LMNA
SCHEMBL13016392 0.77 LMNA (0.41) ALDH1A1MAPTMCL1LMNATSHR
SCHEMBL3919522 0.75 TSHR (0.46) ALDH1A1MAPTLMNATSHR
SCHEMBL10525060 0.75 MCL1 (0.37) ALDH1A1MAPTMCL1LMNA
SCHEMBL8503194 0.74
SCHEMBL10522935 0.74 MCL1 (0.40) ALDH1A1MAPTMCL1LMNA
SCHEMBL6342121 0.74 MCL1 (0.40) ALDH1A1MAPTMCL1LMNA
SCHEMBL10521218 0.73 MCL1 (0.36) ALDH1A1MAPTMCL1LMNATSHR
SCHEMBL9419775 0.72 FFAR3 (0.33) ALDH1A1TSHR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-107075256-A Crosslinkable organopolysiloxane compositions 瓦克化学股份公司 2017-08-18 CN disclosed
US-4554310-A Room temperature vulcanizable organopolysiloxane compositions and method for making GENERAL ELECTRIC COMPANY (US) 1985-11-19 US disclosed
US-4554338-A Room temperature vulcanizable organopolysiloxane compositions and method for making GENERAL ELECTRIC COMPANY (US) 1985-11-19 US disclosed
US-4517337-A ORGANOTIN CATALYST, STABILITY GENERAL ELECTRIC COMPANY (US) 1985-05-14 US disclosed