SCHEMBL915521

SCHEMBL915521

CCNC(=O)C[Si](C)(OC)OC

nearest known ligand 0.39

Predicted protein targets (top 18)

geneUniProtsupporting neighboursconfidence
MCL1 Q07820 1/20 0.39
FAAH O00519 1/20 0.38
MMP1 P03956 1/20 0.32
MMP2 P08253 1/20 0.32
MMP3 P08254 1/20 0.32
MMP9 P14780 1/20 0.32
MMP8 P22894 1/20 0.32
KDM4E B2RXH2 1/20 0.32
RAB9A P51151 3/20 0.32
HPGD P15428 1/20 0.32
NPC1 O15118 1/20 0.32
SMN1; SMN2 Q16637 1/20 0.32
KMT2A Q03164 1/20 0.31
L3MBTL1 Q9Y468 2/20 0.31
LMNA P02545 1/20 0.31
HTT P42858 1/20 0.31
ALDH1A1 P00352 1/20 0.30
KDM4A O75164 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL915166 0.80 MCL1 (0.40) MCL1FAAHMMP1MMP2MMP3
SCHEMBL10940993 0.77 ALDH1A1 (0.35) MCL1LMNAALDH1A1
SCHEMBL8677830 0.77 MCL1 (0.44) MCL1FAAHMMP1MMP2MMP3
SCHEMBL13930299 0.77 MCL1 (0.44) MCL1FAAHMMP1MMP2MMP3
SCHEMBL10524685 0.77 MCL1 (0.44) MCL1FAAHMMP1MMP2MMP3
SCHEMBL14084814 0.75 FAAH (0.58) FAAHHPGD
SCHEMBL3919522 0.72 TSHR (0.46) KDM4EKMT2ALMNAHTTALDH1A1
SCHEMBL9419775 0.69 FFAR3 (0.33) ALDH1A1
SCHEMBL3917867 0.68 GAA (0.50) SMN1; SMN2LMNAALDH1A1
SCHEMBL916845 0.68

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2029661-B1 PROCESS FOR THE PRODUCTION OF HIGH-MOLECULAR-WEIGHT ORGANOPOLYSILOXANES WACKER CHEMIE AG (DE) 2011-08-03 EP disclosed
US-7868116-B2 Process for the production of high-molecular-weight organopolysiloxanes WACKER CHEMIE AG (DE) 2011-01-11 US disclosed
US-7582700-B2 Method for the production of emulsions of highly-viscous organopolysiloxanes WACKER CHEMIE AG (DE) 2009-09-01 US disclosed
US-20090198034-A1 PROCESS FOR THE PRODUCTION OF HIGH-MOLECULAR-WEIGHT ORGANOPOLYSILOXANES WACKER CHEMIE AG (DE) 2009-08-06 US disclosed
EP-1773920-B1 METHOD FOR THE PRODUCTION OF EMULSIONS OF HIGHLY-VISCOUS ORGANOPOLYSILOXANES WACKER CHEMIE AG (DE) 2008-04-09 EP disclosed
US-20080033062-A1 Method for the Production of Emulsions of Highly-Viscous Organopolysiloxanes WACKER CHEMIE AG (DE) 2008-02-07 US disclosed
EP-1773920-A1 METHOD FOR THE PRODUCTION OF EMULSIONS OF HIGHLY-VISCOUS ORGANOPOLYSILOXANES Wacker Chemie AG (DE) 2007-04-18 EP disclosed
WO-2006015740-A1 METHOD FOR THE PRODUCTION OF EMULSIONS OF HIGHLY-VISCOUS ORGANOPOLYSILOXANES WACKER CHEMIE AG (DE) 2006-02-16 WO disclosed