Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA1 | P00915 | 4/20 | 0.56 |
| ▸ | CA2 | P00918 | 4/20 | 0.56 |
| ▸ | CA12 | O43570 | 3/20 | 0.56 |
| ▸ | CA9 | Q16790 | 1/20 | 0.56 |
| ▸ | PKM | P14618 | 1/20 | 0.52 |
| ▸ | POLB | P06746 | 2/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.50 |
| ▸ | RECQL | P46063 | 1/20 | 0.50 |
| ▸ | LMNA | P02545 | 1/20 | 0.49 |
| ▸ | PRMT3 | O60678 | 1/20 | 0.46 |
| ▸ | CARM1 | Q86X55 | 1/20 | 0.46 |
| ▸ | PRMT6 | Q96LA8 | 1/20 | 0.46 |
| ▸ | PRMT1 | Q99873 | 1/20 | 0.46 |
| ▸ | PRMT8 | Q9NR22 | 1/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.45 |
| ▸ | ACHE | P22303 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10486780 | 0.87 | CA1 (0.62) | CA1CA2CA12CA9PKM | |
| SCHEMBL6009330 | 0.86 | ALDH1A1 (0.49) | CA1CA2CA12CA9PKM | |
| SCHEMBL14192213 | 0.83 | CA1 (0.50) | CA1CA2CA12CA9PKM | |
| SCHEMBL9565389 | 0.82 | PRMT3 (0.54) | CA1CA2CA12CA9PKM | |
| SCHEMBL12026291 | 0.80 | CA1 (0.42) | CA1CA2CA12CA9PKM | |
| SCHEMBL11174467 | 0.79 | CA1 (0.54) | CA1CA2CA12CA9PKM | |
| SCHEMBL14192214 | 0.79 | KDM4E (0.45) | PKMALDH1A1RECQLLMNA | |
| SCHEMBL17758464 | 0.77 | KMT2A (0.51) | CA1CA2CA12CA9POLB | |
| SCHEMBL16372128 | 0.77 | LMNA (0.36) | CA1CA2CA12CA9PKM | |
| SCHEMBL15615373 | 0.75 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4500632-A | USING SUBSTITUTED ISOTHIOUREA COMPOUNDS | FUJI PHOTO FILM CO., LTD. (JP) | 1985-02-19 | — | — | US | disclosed |