Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 1/20 | 0.38 |
| ▸ | CTH | P32929 | 1/20 | 0.38 |
| ▸ | CBS | P35520 | 1/20 | 0.38 |
| ▸ | THPO | P40225 | 1/20 | 0.38 |
| ▸ | THRB | P10828 | 1/20 | 0.36 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11088987 | 0.75 | LMNA (0.36) | TSHR | |
| SCHEMBL347044 | 0.75 | TSHR (0.43) | TSHRCTHCBSTHPOTHRB | |
| SCHEMBL11524602 | 0.72 | — | — | |
| SCHEMBL10942864 | 0.70 | — | — | |
| SCHEMBL11472256 | 0.70 | ALDH1A1 (0.47) | TSHRALOX15 | |
| SCHEMBL11087713 | 0.70 | LMNA (0.36) | TSHR | |
| SCHEMBL625594 | 0.70 | LMNA (0.36) | TSHR | |
| Butane SCHEMBL10785306 | 0.65 | PAM (0.36) | TSHRCTHCBSTHPOTHRB | |
| SCHEMBL5029475 | 0.65 | ALDH1A1 (0.33) | TSHR | |
| SCHEMBL28420592 | 0.63 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4550209-A | REACTING TETRAVALENT ZIRCONIUM COMPOUND WITH ORGANO PHOSPHONIC ACID OR ESTER | TEXACO INC. (US) | 1985-10-29 | — | — | US | disclosed |