Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TP53 | P04637 | 4/20 | 0.49 |
| ▸ | HSD17B1 | P14061 | 1/20 | 0.48 |
| ▸ | HSD17B2 | P37059 | 1/20 | 0.48 |
| ▸ | RXFP1 | Q9HBX9 | 2/20 | 0.47 |
| ▸ | CES2 | O00748 | 1/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.47 |
| ▸ | TACR1 | P25103 | 2/20 | 0.46 |
| ▸ | MAPT | P10636 | 3/20 | 0.45 |
| ▸ | HTT | P42858 | 1/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.45 |
| ▸ | POLQ | O75417 | 1/20 | 0.45 |
| ▸ | POLB | P06746 | 2/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.42 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.42 |
| ▸ | RAB9A | P51151 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28141847 | 0.85 | TP53 (0.50) | TP53HSD17B1HSD17B2RXFP1CES2 | |
| SCHEMBL11174926 | 0.85 | TACR1 (0.50) | TP53HSD17B1HSD17B2RXFP1CES2 | |
| SCHEMBL8601016 | 0.83 | TP53 (0.49) | TP53HSD17B1HSD17B2RXFP1CES2 | |
| SCHEMBL12220665 | 0.81 | RXFP1 (0.54) | TP53HSD17B1HSD17B2RXFP1CES2 | |
| SCHEMBL28746553 | 0.81 | MLYCD (0.54) | TP53HSD17B1HSD17B2RXFP1CES2 | |
| SCHEMBL7675880 | 0.81 | TP53 (0.54) | TP53HSD17B1HSD17B2RXFP1CES2 | |
| SCHEMBL11402034 | 0.81 | POLQ (0.52) | TP53HSD17B1HSD17B2RXFP1CES2 | |
| SCHEMBL12544171 | 0.80 | NR1H3 (0.57) | HSD17B1HSD17B2RXFP1CES2ALDH1A1 | |
| SCHEMBL7535315 | 0.80 | EGFR (0.50) | TP53HSD17B1HSD17B2RXFP1CES2 | |
| SCHEMBL514284 | 0.80 | HSD17B1 (0.48) | TP53HSD17B1HSD17B2RXFP1CES2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4554015-A | THIOCARBAMATES | TOYO SODA MANUFACTURING CO., LTD. (JP) | 1985-11-19 | — | — | US | disclosed |