Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLQ | O75417 | 7/20 | 0.52 |
| ▸ | TACR1 | P25103 | 2/20 | 0.51 |
| ▸ | TP53 | P04637 | 2/20 | 0.47 |
| ▸ | HSD17B1 | P14061 | 1/20 | 0.46 |
| ▸ | HSD17B2 | P37059 | 1/20 | 0.46 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.46 |
| ▸ | CES2 | O00748 | 1/20 | 0.45 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.44 |
| ▸ | MAPT | P10636 | 2/20 | 0.43 |
| ▸ | HTT | P42858 | 1/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
| ▸ | POLB | P06746 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14955365 | 0.86 | POLQ (0.51) | POLQTACR1TP53HSD17B1HSD17B2 | |
| SCHEMBL967785 | 0.85 | POLQ (0.50) | POLQTACR1TP53HSD17B1HSD17B2 | |
| SCHEMBL11406952 | 0.83 | TACR1 (0.60) | POLQTACR1CES2 | |
| SCHEMBL11174926 | 0.82 | TACR1 (0.50) | POLQTACR1TP53HSD17B1HSD17B2 | |
| SCHEMBL28141847 | 0.82 | TP53 (0.50) | POLQTACR1TP53HSD17B1HSD17B2 | |
| SCHEMBL8601016 | 0.81 | TP53 (0.49) | POLQTACR1TP53HSD17B1HSD17B2 | |
| SCHEMBL10943479 | 0.81 | TP53 (0.49) | POLQTACR1TP53HSD17B1HSD17B2 | |
| SCHEMBL9357893 | 0.81 | LMNA (0.57) | POLQTACR1TP53HSD17B1HSD17B2 | |
| SCHEMBL11401944 | 0.80 | POLQ (0.52) | POLQTACR1CES2SMN1; SMN2LMNA | |
| SCHEMBL11351438 | 0.79 | GPBAR1 (0.41) | CES2ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0037938-A1 | Substituted acetanilides, process for their preparation and their utilization as herbicides | NIHON TOKUSHU NOYAKU SEIZO K.K. (JP) | 1981-10-21 | — | — | EP | disclosed |