Known targets — ChEMBL curated mechanism
ADRA1AADRA1BADRA1DADRA2AADRA2BADRA2CADRB1ADRB2ADRB3CALCRLCHRM1CHRM2CHRM3F2RMAOAMAOBMAP2K1MAP2K2NTRK1NTRK2NTRK3OPRD1OPRK1OPRM1P2RY12PKLRSCN10ASCN11ASCN1ASCN2ASCN3ASCN4ASCN5ASCN7ASCN8ASCN9ASLC18A2SLC6A2SLC6A3TLR7TLR9TUBA1ATUBA1BTUBA1CTUBA3CTUBA3ETUBA4ATUBBTUBB1TUBB2ATUBB2BTUBB3TUBB4ATUBB4BTUBB6TUBB8dacAdacBdacCfolAftsImrcAmrcBmrdApolrplArplBrplCrplDrplErplFrplIrplJrplKrplLrplMrplNrplOrplPrplQrplRrplSrplTrplUrplVrplWrplXrplYrpmArpmBrpmB1rpmB2rpmCrpmDrpmErpmE2rpmFrpmGrpmG1rpmG2rpmHrpmIrpmJrpmJ2rpsArpsBrpsCrpsDrpsErpsFrpsGrpsHrpsIrpsJrpsKrpsLrpsMrpsNrpsOrpsPrpsQrpsRrpsR1rpsR2rpsSrpsTrpsUrpsZykgMykgO
The experimentally established mechanism targets of Sulfuric Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.53 |
| ▸ | TP53 | P04637 | 1/20 | 0.53 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.53 |
| ▸ | THRB | P10828 | 1/20 | 0.53 |
| ▸ | HPGD | P15428 | 1/20 | 0.53 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.53 |
| ▸ | CASP1 | P29466 | 1/20 | 0.53 |
| ▸ | RECQL | P46063 | 1/20 | 0.53 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.53 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.53 |
| ▸ | CA2 | P00918 | 5/20 | 0.48 |
| ▸ | CA12 | O43570 | 4/20 | 0.48 |
| ▸ | CA1 | P00915 | 4/20 | 0.48 |
| ▸ | HTR6 | P50406 | 4/20 | 0.47 |
| ▸ | PKM | P14618 | 1/20 | 0.47 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.47 |
| ▸ | CA9 | Q16790 | 3/20 | 0.45 |
| ▸ | TSHR | P16473 | 2/20 | 0.44 |
| ▸ | NT5E | P21589 | 1/20 | 0.44 |
| ▸ | DHFR | P00374 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Sulfuric Acid SCHEMBL10944454 | 0.95 | ALDH1A1 (0.55) | ALDH1A1TP53CYP3A4THRBHPGD | |
| Sulfuric Acid SCHEMBL5843672 | 0.89 | ALDH1A1 (0.65) | ALDH1A1TP53CYP3A4THRBHPGD | |
| Sulfuric Acid SCHEMBL8863657 | 0.87 | CA2 (0.50) | ALDH1A1TP53CYP3A4THRBHPGD | |
| Sulfuric Acid SCHEMBL8366265 | 0.87 | ALDH1A1 (0.63) | ALDH1A1TP53CYP3A4THRBHPGD | |
| Sulfuric Acid SCHEMBL9283147 | 0.87 | ALDH1A1 (0.63) | ALDH1A1TP53CYP3A4THRBHPGD | |
| Sulfuric Acid SCHEMBL9236320 | 0.85 | ALDH1A1 (0.61) | ALDH1A1TP53CYP3A4THRBHPGD | |
| Sulfuric Acid SCHEMBL8906572 | 0.81 | THRB (0.81) | ALDH1A1TP53CYP3A4THRBHPGD | |
| Sulfuric Acid SCHEMBL16207785 | 0.78 | ALDH1A1 (0.81) | ALDH1A1TP53CYP3A4THRBHPGD | |
| Sulfuric Acid SCHEMBL4610500 | 0.77 | ALDH1A1 (0.72) | ALDH1A1TP53CYP3A4THRBHPGD | |
| Sulfuric Acid SCHEMBL10407296 | 0.77 | ALDH1A1 (0.52) | ALDH1A1TP53CYP3A4THRBHPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4526853-A | Silver halide color photographic material comprising emulsion layer, brightening agent layer, ultraviolet absorber layer | KONISHIROKU PHOTO INDUSTRY CO., LTD. (JP) | 1985-07-02 | — | — | US | disclosed |