SCHEMBL10944985

SCHEMBL10944985

CN(C)CCNC(=S)Nc1ccccc1

nearest known ligand 0.71

Predicted protein targets (top 18)

geneUniProtsupporting neighboursconfidence
LMNA P02545 2/20 0.71
POLB P06746 2/20 0.71
KMT2A Q03164 4/20 0.70
MEN1 O00255 1/20 0.70
ALDH1A1 P00352 2/20 0.68
SMN1; SMN2 Q16637 2/20 0.63
CA12 O43570 1/20 0.62
CA1 P00915 1/20 0.62
CA2 P00918 1/20 0.62
RAB9A P51151 3/20 0.60
NPC1 O15118 2/20 0.60
MAOA P21397 1/20 0.60
MAOB P27338 1/20 0.60
GAA P10253 1/20 0.59
MAPT P10636 1/20 0.59
ALOX12 P18054 1/20 0.59
L3MBTL1 Q9Y468 1/20 0.58
KDM4E B2RXH2 1/20 0.57

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4397577 0.90 ALDH1A1 (0.83) LMNAPOLBKMT2AMEN1ALDH1A1
SCHEMBL8956279 0.83 KMT2A (0.78) LMNAKMT2AMEN1ALDH1A1SMN1; SMN2
SCHEMBL10941979 0.82 KMT2A (0.71) LMNAPOLBKMT2AMEN1ALDH1A1
SCHEMBL20109299 0.80 KMT2A (0.68) LMNAKMT2AMEN1ALDH1A1RAB9A
SCHEMBL5458013 0.80 KMT2A (1.00) LMNAKMT2AMEN1ALDH1A1RAB9A
SCHEMBL2597849 0.79 HTT (0.64) LMNAPOLBKMT2AMEN1ALDH1A1
SCHEMBL17079619 0.79 L3MBTL1 (0.69) LMNAPOLBKMT2AMEN1ALDH1A1
SCHEMBL18243810 0.79 KMT2A (0.71) LMNAKMT2AMEN1ALDH1A1SMN1; SMN2
SCHEMBL5138189 0.78 KMT2A (0.73) LMNAKMT2AMEN1ALDH1A1RAB9A
SCHEMBL14868396 0.77 KMT2A (0.63) LMNAPOLBKMT2AMEN1ALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2025024883-A1 NOVEL BROAD SPECTRUM ANTIVIRAL AND ANTIMICROBIAL PEPTIDE MIMICS NEWSOUTH INNOVATIONS PTY LIMITED (AU) 2025-02-06 WO disclosed
US-4500632-A USING SUBSTITUTED ISOTHIOUREA COMPOUNDS FUJI PHOTO FILM CO., LTD. (JP) 1985-02-19 US disclosed