SCHEMBL4397577

SCHEMBL4397577

CN(C)CCCNC(=S)Nc1ccccc1

nearest known ligand 0.83

Predicted protein targets (top 18)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 5/20 0.83
SMN1; SMN2 Q16637 1/20 0.77
LMNA P02545 4/20 0.63
GAA P10253 4/20 0.63
KMT2A Q03164 4/20 0.63
MEN1 O00255 1/20 0.59
POLB P06746 2/20 0.59
RAB9A P51151 3/20 0.57
NPC1 O15118 2/20 0.57
MAOA P21397 1/20 0.57
MAOB P27338 1/20 0.57
MAPT P10636 2/20 0.56
ALOX12 P18054 1/20 0.56
L3MBTL1 Q9Y468 1/20 0.55
APOBEC3G Q9HC16 1/20 0.55
HPGD P15428 1/20 0.55
HTT P42858 1/20 0.54
NPSR1 Q6W5P4 1/20 0.54

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10944985 0.90 LMNA (0.71) ALDH1A1SMN1; SMN2LMNAGAAKMT2A
SCHEMBL5448339 0.83 KMT2A (0.67) ALDH1A1SMN1; SMN2LMNAGAAKMT2A
SCHEMBL4575974 0.83 LMNA (0.87) ALDH1A1SMN1; SMN2LMNAGAAKMT2A
SCHEMBL11831458 0.83 ALDH1A1 (0.60) ALDH1A1SMN1; SMN2LMNAGAAPOLB
SCHEMBL3958934 0.81 KMT2A (0.80) ALDH1A1SMN1; SMN2LMNAGAAKMT2A
SCHEMBL17595823 0.81 LMNA (0.79) ALDH1A1SMN1; SMN2LMNAGAAKMT2A
SCHEMBL7507650 0.81 EPHX1 (0.65) ALDH1A1SMN1; SMN2LMNAPOLBHTT
SCHEMBL8956279 0.80 KMT2A (0.78) ALDH1A1SMN1; SMN2LMNAGAAKMT2A
SCHEMBL11438307 0.80 KMT2A (0.77) ALDH1A1SMN1; SMN2LMNAGAAKMT2A
SCHEMBL5138189 0.79 KMT2A (0.73) ALDH1A1LMNAGAAKMT2AMEN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 24 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3916074-B1 SYNERGISTIC ANTIKNOCK FUEL ADDITIVE AND GASOLINE COMPOSITION COMPRISING THE SAME REPSOL SA (ES) 2023-07-05 EP disclosed
EP-3943580-A1 GASOLINE COMPOSITION COMPRISING INDOLINE Repsol, S.A. (ES) 2022-01-26 EP disclosed
WO-2021239755-A1 SYNERGISTIC ANTIKNOCK FUEL ADDITIVE AND GASOLINE COMPOSITION COMPRISING THE SAME REPSOL, S.A. (ES) 2021-12-02 WO disclosed
EP-3916074-A1 SYNERGISTIC ANTIKNOCK FUEL ADDITIVE AND GASOLINE COMPOSITION COMPRISING THE SAME Repsol, S.A. (ES) 2021-12-01 EP disclosed
CN-105579436-B Onium salts and compositions comprising the same 旭化成株式会社 2020-12-22 CN disclosed
US-10189781-B2 Onium salt and composition comprising the same ASAHI KASEI E-MATERIALS CORPORATION (JP) 2019-01-29 US disclosed
US-20160229801-A1 ONIUM SALT AND COMPOSITION COMPRISING THE SAME ASAHI KASEI E-MATERIALS CORPORATION (JP) 2016-08-11 US disclosed
US-9028942-B2 Fluoroelastomer composition and molded article DAIKIN INDUSTRIES, LTD. (JP) 2015-05-12 US disclosed
EP-2607424-A1 FLUOROELASTOMER COMPOSITION AND MOLDED ARTICLE Daikin Industries, Ltd. (JP) 2013-06-26 EP disclosed
US-20130150503-A1 FLUOROELASTOMER COMPOSITION AND MOLDED ARTICLE DAIKIN INDUSTRIES, LTD. (JP) 2013-06-13 US disclosed
EP-1368029-A4 METHOD AND COMPOSITION FOR REJUVINATING CELLS, TISSUES, ORGANS, HAIR AND NAILS FARRINGTON PHARMACEUTICALS LLC (US) 2006-02-15 EP disclosed
US-20050245512-A1 Method and composition for rejuvinating cells, tissues organs, hair and nails ULRICH PETER C 2005-11-03 US disclosed
US-20050222226-A1 Five-membered cyclic compounds SUMITOMO PHARMACEUTICALS COMPANY, LIMITED 2005-10-06 US disclosed
US-6919361-B2 Five-membered-ring compound SUMITOMO PHARMACEUTICALS COMPANY, LIMITED (JP) 2005-07-19 US disclosed
US-6777557-B2 Method and composition for rejuvenating cells, tissues organs, hair and nails FARRINGTON PHARMACEUTICALS, LLC 2004-08-17 US disclosed
US-20040072827-A1 Five-membered-ring compound SUMITOMO DAINIPPON PHARMA CO., LTD. (JP) 2004-04-15 US disclosed
EP-1368029-A2 METHOD AND COMPOSITION FOR REJUVINATING CELLS, TISSUES, ORGANS, HAIR AND NAILS Farrington Pharmaceuticals, LLC (US) 2003-12-10 EP disclosed
EP-1300401-A1 FIVE-MEMBERED-RING COMPOUND SUMITOMO PHARMACEUTICALS COMPANY, LIMITED (JP) 2003-04-09 EP disclosed
US-20020188015-A1 Method and composition for rejuvinating cells, tissues organs, hair and nails FARRINGTON PHARMACEUTICALS, LLC 2002-12-12 US disclosed
WO-2002062301-A2 METHOD AND COMPOSITION FOR REJUVINATING CELLS, TISSUES, ORGANS, HAIR AND NAILS FARRINGTON PHARMACEUTICALS, LLC (US) 2002-08-15 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (6 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20040072827-A1 Five-membered-ring compound EPX, IL5, CCR9 ALDH1A1 3257/4885SMN1; SMN2 3887/4885LMNA 4315/4885
US-20020188015-A1 Method and composition for rejuvinating cells, tissues organs, hair and nails TERT, TELO2, HKDC1 ALDH1A1 3396/4885SMN1; SMN2 2608/4885LMNA 820/4885
US-20050245512-A1 Method and composition for rejuvinating cells, tissues organs, hair and nails TERT, TELO2, HKDC1 ALDH1A1 3396/4885SMN1; SMN2 2608/4885LMNA 820/4885
US-20050222226-A1 Five-membered cyclic compounds EPX, CCL11, CCR9 ALDH1A1 3404/4885SMN1; SMN2 3889/4885LMNA 3956/4885
US-10189781-B2 Onium salt and composition comprising the same EIF2B5, HSF1, INPP5A ALDH1A1 3019/4885SMN1; SMN2 1112/4885LMNA 2098/4885
US-20160229801-A1 ONIUM SALT AND COMPOSITION COMPRISING THE SAME EIF2B5, HSF1, INPP5A ALDH1A1 3019/4885SMN1; SMN2 1112/4885LMNA 2098/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.