Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 6/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.42 |
| ▸ | GAA | P10253 | 3/20 | 0.42 |
| ▸ | HPGD | P15428 | 3/20 | 0.42 |
| ▸ | MAPT | P10636 | 2/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.42 |
| ▸ | GFER | P55789 | 1/20 | 0.42 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.42 |
| ▸ | P2RX7 | Q99572 | 2/20 | 0.39 |
| ▸ | RAB9A | P51151 | 2/20 | 0.36 |
| ▸ | NPC1 | O15118 | 1/20 | 0.36 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 5/20 | 0.36 |
| ▸ | GLA | P06280 | 1/20 | 0.36 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.36 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
| ▸ | POLB | P06746 | 1/20 | 0.34 |
| ▸ | MAOA | P21397 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18218044 | 0.81 | KMT2A (0.41) | KMT2AALDH1A1GAAHPGDMAPT | |
| SCHEMBL18489284 | 0.80 | RAB9A (0.46) | KMT2AALDH1A1GAAHPGDMAPT | |
| SCHEMBL24658715 | 0.76 | PYCR1 (0.34) | — | |
| SCHEMBL17449532 | 0.69 | TAAR1 (0.43) | GAAMAPTKDM4EHSD17B10RAB9A | |
| SCHEMBL852004 | 0.69 | ALDH1A1 (0.39) | KMT2AALDH1A1GAAHPGDMAPT | |
| SCHEMBL12203849 | 0.67 | TAAR1 (0.42) | KMT2AALDH1A1GAAHPGDMAPT | |
| SCHEMBL4006982 | 0.67 | ALDH1A1 (0.40) | KMT2AALDH1A1GAAHPGDMAPT | |
| Biphenyl SCHEMBL164 | 0.60 | ALDH1A1 (1.00) | ALDH1A1MAPTHSD17B10RAB9ANPC1 | |
| Biphenyl SCHEMBL2548048 | 0.60 | ALDH1A1 (1.00) | ALDH1A1MAPTHSD17B10RAB9ANPC1 | |
| Biphenyl SCHEMBL4002609 | 0.60 | ALDH1A1 (1.00) | ALDH1A1MAPTHSD17B10RAB9ANPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4494547-A | 2H-isoindolediones, their synthesis and use as radiosensitizers | NORTH CAROLINA CENTRAL UNIVERSITY (US) | 1985-01-22 | — | — | US | disclosed |