Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.40 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.38 |
| ▸ | GAA | P10253 | 2/20 | 0.38 |
| ▸ | MAPT | P10636 | 2/20 | 0.38 |
| ▸ | HPGD | P15428 | 2/20 | 0.38 |
| ▸ | MEN1 | O00255 | 2/20 | 0.38 |
| ▸ | GLA | P06280 | 1/20 | 0.38 |
| ▸ | RAB9A | P51151 | 2/20 | 0.38 |
| ▸ | NPC1 | O15118 | 1/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.38 |
| ▸ | NISCH | Q9Y2I1 | 1/20 | 0.38 |
| ▸ | HTR1D | P28221 | 1/20 | 0.37 |
| ▸ | HTR2C | P28335 | 1/20 | 0.37 |
| ▸ | HTR2B | P41595 | 1/20 | 0.37 |
| ▸ | HTR3A | P46098 | 1/20 | 0.37 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
| ▸ | GFER | P55789 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10945637 | 0.67 | KMT2A (0.42) | ALDH1A1KMT2AGAAMAPTHPGD | |
| Biphenyl SCHEMBL28376025 | 0.65 | ALDH1A1 (0.60) | ALDH1A1MAPTRAB9ANPC1MAPK1 | |
| SCHEMBL21191540 | 0.64 | NISCH (0.35) | ALDH1A1KMT2AGAAMAPTHPGD | |
| Biphenyl SCHEMBL27765460 | 0.64 | ALDH1A1 (0.69) | ALDH1A1MAPTRAB9ANPC1MAPK1 | |
| SCHEMBL24365675 | 0.63 | NISCH (0.42) | ALDH1A1KMT2AGAAMAPTHPGD | |
| Biphenyl SCHEMBL653702 | 0.62 | ALDH1A1 (0.82) | ALDH1A1MAPTRAB9ANPC1MAPK1 | |
| Biphenyl SCHEMBL21462355 | 0.61 | ALDH1A1 (0.53) | ALDH1A1GAAMAPTRAB9ANPC1 | |
| Biphenyl SCHEMBL2548048 | 0.61 | ALDH1A1 (1.00) | ALDH1A1MAPTRAB9ANPC1MAPK1 | |
| Biphenyl SCHEMBL1358618 | 0.61 | ALDH1A1 (1.00) | ALDH1A1MAPTRAB9ANPC1MAPK1 | |
| Biphenyl SCHEMBL164 | 0.61 | ALDH1A1 (1.00) | ALDH1A1MAPTRAB9ANPC1MAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1735266-B1 | PROCESS FOR PREPARATION OF OPTICALLY ACTIVE 1-ERYTHRO-2-AMINO-1-PHENYL-1-PROPANOL | EMMELLEN BIOTECH PHARMACEUTICA (IN) | 2009-06-24 | — | — | EP | disclosed |
| US-7414153-B2 | Process for preparation of optically active 1-erythro-2-amino-1-phenyl-1-propanol | EMMELLEN BIOTECH PHARMACEUTICALS LIMITED (IN) | 2008-08-19 | — | — | US | disclosed |
| US-20070203363-A1 | Process For Preparation Of Optically Active 1-Erythro-2-Amino-1-Phenyl-1-Propanol | EMMELLEN BIOTECH PHARMACEUTICALS LIMITED (IN) | 2007-08-30 | — | — | US | disclosed |
| EP-1735266-A1 | PROCESS FOR PREPARATION OF OPTICALLY ACTIVE 1-ERYTHRO-2-AMINO-1-PHENYL-1-PROPANOL | Emmellen Biotech Pharmaceuticals Limited (IN) | 2006-12-27 | — | — | EP | disclosed |
| WO-2005100299-A1 | PROCESS FOR PREPARATION OF OPTICALLY ACTIVE 1-ERYTHRO-2-AMINO-1-PHENYL-1-PROPANOL | EMMELLEN BIOTECH PHARMACEUTICALS LIMITED (IN) | 2005-10-27 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070203363-A1 | Process For Preparation Of Optically Active 1-Erythro-2-Amino-1-Phenyl-1-Propanol | HMOX1, HMOX2, OXER1 | ALDH1A1 312/4885CHRM1 454/4885KMT2A 794/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.