Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BRD4 | O60885 | 1/20 | 0.47 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.46 |
| ▸ | CTNNB1 | P35222 | 1/20 | 0.45 |
| ▸ | TSPO | P30536 | 1/20 | 0.44 |
| ▸ | LMNA | P02545 | 2/20 | 0.43 |
| ▸ | MAPT | P10636 | 2/20 | 0.43 |
| ▸ | IKBKB | O14920 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.43 |
| ▸ | GAA | P10253 | 2/20 | 0.43 |
| ▸ | POLB | P06746 | 2/20 | 0.43 |
| ▸ | RAB9A | P51151 | 2/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.43 |
| ▸ | GLA | P06280 | 1/20 | 0.43 |
| ▸ | HPGD | P15428 | 1/20 | 0.43 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.42 |
| ▸ | ATM | Q13315 | 1/20 | 0.42 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6062389 | 0.83 | GAA (0.54) | ADRA2CTSPOLMNAMAPTALDH1A1 | |
| SCHEMBL7719997 | 0.83 | L3MBTL1 (0.54) | BRD4ADRA2CTSPOLMNAMAPT | |
| SCHEMBL27496561 | 0.82 | POLB (0.49) | CTNNB1TSPOLMNAMAPTALDH1A1 | |
| SCHEMBL3450491 | 0.81 | ALDH1A1 (0.47) | LMNAMAPTALDH1A1POLBRAB9A | |
| Acetic Acid SCHEMBL7835964 | 0.79 | GAA (0.56) | BRD4ADRA2CCTNNB1TSPOLMNA | |
| SCHEMBL3175163 | 0.78 | BRD4 (0.63) | BRD4LMNAMAPTGAAL3MBTL1 | |
| SCHEMBL11086850 | 0.78 | CAMK2A (0.52) | ADRA2CTSPOLMNAMAPTALDH1A1 | |
| SCHEMBL3728925 | 0.78 | ALDH1A1 (0.56) | MAPTIKBKBALDH1A1GAARAB9A | |
| SCHEMBL6063201 | 0.76 | LMNA (0.45) | ADRA2CTSPOLMNAMAPTALDH1A1 | |
| SCHEMBL9474878 | 0.76 | HDAC1 (0.45) | ALDH1A1GAAL3MBTL1KDM4EGLA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0105660-B1 | PREPARATION OF BIS-(AMINOPHENYL) ETHERS FROM (N-ACETYL) AMINOPHENOLS OR THEIR PHENOLATES | MALLINCKRODT, INC.(a Missouri corporation) (US) | 1985-11-27 | — | — | EP | disclosed |
| US-4551551-A | Preparation of bis(aminophenyl) ethers from (N-acetyl)aminophenols or their phenolates | MALLINCKRODT, INC. (US) | 1985-11-05 | — | — | US | disclosed |
| EP-0105660-A1 | Preparation of bis-(aminophenyl) ethers from (N-acetyl) aminophenols or their phenolates | MALLINCKRODT, INC.(a Missouri corporation) (US) | 1984-04-18 | — | — | EP | disclosed |