Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 1/20 | 0.45 |
| ▸ | MAPT | P10636 | 1/20 | 0.45 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.43 |
| ▸ | POLB | P06746 | 2/20 | 0.43 |
| ▸ | ATM | Q13315 | 1/20 | 0.43 |
| ▸ | NPC1 | O15118 | 1/20 | 0.43 |
| ▸ | RAB9A | P51151 | 1/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.43 |
| ▸ | MAPK8 | P45983 | 2/20 | 0.43 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.41 |
| ▸ | TSPO | P30536 | 3/20 | 0.40 |
| ▸ | GAA | P10253 | 3/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
| ▸ | RIPK1 | Q13546 | 1/20 | 0.39 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.39 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11086850 | 0.84 | CAMK2A (0.52) | LMNAMAPTL3MBTL1POLBATM | |
| SCHEMBL11092427 | 0.79 | MAPT (0.45) | LMNAMAPTL3MBTL1POLBATM | |
| SCHEMBL7719997 | 0.77 | L3MBTL1 (0.54) | LMNAMAPTL3MBTL1POLBATM | |
| SCHEMBL6062389 | 0.77 | GAA (0.54) | LMNAMAPTL3MBTL1POLBATM | |
| SCHEMBL10945752 | 0.76 | BRD4 (0.47) | LMNAMAPTL3MBTL1POLBATM | |
| SCHEMBL27496561 | 0.76 | POLB (0.49) | LMNAMAPTL3MBTL1POLBRAB9A | |
| SCHEMBL2342698 | 0.70 | ADRA2C (0.64) | LMNAMAPTL3MBTL1POLBATM | |
| SCHEMBL30327328 | 0.70 | ADRA2C (0.64) | LMNAMAPTL3MBTL1POLBATM | |
| SCHEMBL13028245 | 0.69 | POLB (0.51) | LMNAMAPTL3MBTL1POLBATM | |
| SCHEMBL14273051 | 0.68 | L3MBTL1 (0.64) | MAPTL3MBTL1POLBSMN1; SMN2TDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7145035-B2 | Methods of ortho alkylation | E. I. DU PONT DE NEMOURS AND COMPANY (US) | 2006-12-05 | — | — | US | disclosed |
| US-20040082793-A1 | Methods of ortho alkylation | E. I. DU PONT DE NEMOURS AND COMPANY | 2004-04-29 | — | — | US | disclosed |
| EP-1368310-A2 | IMPROVED METHODS OF ORTHO ALKYLATION | E. I. du Pont de Nemours and Company (US) | 2003-12-10 | — | — | EP | disclosed |
| WO-2002072540-A2 | IMPROVED METHODS OF ORTHO ALKYLATION | E. I. DU PONT DE NEMOURS AND COMPANY (US) | 2002-09-19 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040082793-A1 | Methods of ortho alkylation | CBR1, AOC2, CBR3 | LMNA 2756/4885MAPT 4467/4885L3MBTL1 1209/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.