Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CES1 | P23141 | 7/20 | 0.48 |
| ▸ | CA2 | P00918 | 1/20 | 0.41 |
| ▸ | CA4 | P22748 | 1/20 | 0.41 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.37 |
| ▸ | FAAH | O00519 | 3/20 | 0.36 |
| ▸ | HDAC6 | Q9UBN7 | 2/20 | 0.36 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.36 |
| ▸ | CES2 | O00748 | 1/20 | 0.36 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.35 |
| ▸ | CPA1 | P15085 | 1/20 | 0.35 |
| ▸ | KCNN1 | Q92952 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Bicarbonate SCHEMBL2810754 | 0.82 | CA2 (0.50) | CES1CA2CA4HDAC6MAPK1 | |
| Trifluoroacetic Acid SCHEMBL30358955 | 0.79 | CES1 (0.46) | CES1CA2CA4PTPN1FAAH | |
| Trifluoroacetic Acid SCHEMBL11226934 | 0.79 | CES1 (0.46) | CES1CA2CA4PTPN1FAAH | |
| Trifluoroacetic Acid SCHEMBL15355498 | 0.79 | APOBEC3A (0.54) | CES1CA2CA4 | |
| Trifluoroacetic Acid SCHEMBL107376 | 0.77 | CES1 (0.45) | CES1CA2CA4PTPN1FAAH | |
| Trifluoroacetic Acid SCHEMBL107133 | 0.77 | CES1 (0.45) | CES1CA2CA4PTPN1FAAH | |
| Trifluoroacetic Acid SCHEMBL8055878 | 0.77 | TDP1 (0.52) | CES1CA2CA4PTPN1FAAH | |
| Trifluoroacetic Acid SCHEMBL7973718 | 0.77 | CES1 (0.45) | CES1CA2CA4PTPN1FAAH | |
| Tetraphenylphosphonium SCHEMBL7931793 | 0.77 | CES1 (0.45) | CES1CA2CA4PTPN1FAAH | |
| Trifluoroacetic Acid SCHEMBL10925867 | 0.77 | CES1 (0.45) | CES1CA2CA4PTPN1FAAH |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4522758-A | Method of preparing 2-fluoro-17β-estradiol | ELI LILLY AND COMPANY (US) | 1985-06-11 | — | — | US | disclosed |
| US-4268682-A | ω-Alkenyl silanes and αω-silyl alkanes | EXXON RESEARCH & ENGINEERING CO. (US) | 1981-05-19 | — | — | US | disclosed |
| US-4220556-A | HETEROGENEOUS CATALYST COVALENTLY ANCHORED TO CATALYST SUPPORT | EXXON RESEARCH & ENGINEERING CO. (US) | 1980-09-02 | — | — | US | disclosed |
| US-4151114-A | ANCHORED CATALYSTS | EXXON RESEARCH & ENGINEERING CO. (US) | 1979-04-24 | — | — | US | disclosed |
| US-4134906-A | Silylhydrocarbyl phosphine transition metal complexes | EXXON RESEARCH & ENGINEERING CO. (US) | 1979-01-16 | — | — | US | disclosed |
| US-4083803-A | Anchored silylhydrocarbyl phosphine transition metal complex catalysts and their method of preparation | EXXON RESEARCH & ENGINEERING CO. (US) | 1978-04-11 | — | — | US | disclosed |