Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LTA4H | P09960 | 1/20 | 0.52 |
| ▸ | SRD5A2 | P31213 | 1/20 | 0.51 |
| ▸ | PTGS2 | P35354 | 4/20 | 0.50 |
| ▸ | LMNA | P02545 | 3/20 | 0.49 |
| ▸ | HTT | P42858 | 3/20 | 0.49 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.49 |
| ▸ | CA12 | O43570 | 1/20 | 0.49 |
| ▸ | CA1 | P00915 | 1/20 | 0.49 |
| ▸ | CA2 | P00918 | 1/20 | 0.49 |
| ▸ | CA9 | Q16790 | 1/20 | 0.49 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.49 |
| ▸ | SOS1 | Q07889 | 1/20 | 0.49 |
| ▸ | NR3C1 | P04150 | 2/20 | 0.46 |
| ▸ | PGR | P06401 | 2/20 | 0.46 |
| ▸ | PTGES | O14684 | 1/20 | 0.46 |
| ▸ | PTGS1 | P23219 | 2/20 | 0.46 |
| ▸ | ACACB | O00763 | 1/20 | 0.45 |
| ▸ | ACACA | Q13085 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16770523 | 0.89 | CA12 (0.58) | LTA4HPTGS2LMNACA12CA1 | |
| SCHEMBL19341781 | 0.86 | HTT (0.53) | PTGS2LMNAHTTSMN1; SMN2NR3C1 | |
| SCHEMBL7359540 | 0.85 | SOS1 (0.64) | LTA4HPTGS2LMNAHTTSMN1; SMN2 | |
| SCHEMBL11308959 | 0.85 | PSIP1 (0.55) | LTA4HSRD5A2LMNAHTTSMN1; SMN2 | |
| SCHEMBL13407573 | 0.82 | HTT (0.76) | LTA4HSRD5A2LMNAHTTSMN1; SMN2 | |
| SCHEMBL13155652 | 0.82 | HTT (0.61) | PTGS2LMNAHTTSMN1; SMN2NR3C1 | |
| SCHEMBL13443418 | 0.82 | HTT (0.76) | LTA4HSRD5A2LMNAHTTSMN1; SMN2 | |
| SCHEMBL16610346 | 0.82 | HTT (0.61) | PTGS2LMNAHTTSMN1; SMN2NR3C1 | |
| SCHEMBL246373 | 0.81 | LTA4H (0.67) | LTA4HSRD5A2HTTACACBACACA | |
| SCHEMBL7178244 | 0.81 | LTA4H (0.67) | LTA4HSRD5A2HTTACACBACACA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4349568-A | Sulfur-substituted diphenyl ethers having antiviral activity | THE DOW CHEMICAL COMPANY (US) | 1982-09-14 | — | — | US | claimed |
| US-4505929-A | Sulfur-substituted diphenyl ethers having antiviral activity | THE DOW CHEMICAL COMPANY (US) | 1985-03-19 | — | — | US | disclosed |
| US-4349568-A | Sulfur-substituted diphenyl ethers having antiviral activity | THE DOW CHEMICAL COMPANY (US) | 1982-09-14 | — | — | US | disclosed |