Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA12 | O43570 | 1/20 | 0.58 |
| ▸ | CA1 | P00915 | 1/20 | 0.58 |
| ▸ | CA2 | P00918 | 1/20 | 0.58 |
| ▸ | CA9 | Q16790 | 1/20 | 0.58 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.58 |
| ▸ | PTGS2 | P35354 | 10/20 | 0.53 |
| ▸ | CALM1 | P0DP23 | 1/20 | 0.52 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.51 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.51 |
| ▸ | LMNA | P02545 | 1/20 | 0.48 |
| ▸ | LTA4H | P09960 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13231429 | 0.91 | ENPP2 (0.54) | CA12CA1CA2CA9CA14 | |
| SCHEMBL10947465 | 0.89 | LTA4H (0.52) | CA12CA1CA2CA9CA14 | |
| SCHEMBL22233466 | 0.82 | CA1 (0.62) | CA12CA1CA2CA9CA14 | |
| SCHEMBL21165326 | 0.82 | CA2 (0.66) | CA12CA1CA2CA9CA14 | |
| SCHEMBL17737828 | 0.81 | IDO1 (0.49) | CA12CA1CA2CA9CA14 | |
| SCHEMBL7935589 | 0.81 | PTGS2 (0.56) | PTGS2PTGS1 | |
| SCHEMBL7938035 | 0.81 | ENPP2 (0.75) | CA12CA1CA2CA9PTGS2 | |
| SCHEMBL17071839 | 0.80 | PTGS2 (0.47) | CA1CA2CA9PTGS2GRIN2B | |
| SCHEMBL17069270 | 0.80 | PTGS2 (0.47) | CA1CA2CA9PTGS2PTGS1 | |
| Diphenylmethane SCHEMBL9244248 | 0.79 | CALM1 (0.60) | CA12CA1CA2CA9CA14 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2015078374-A1 | SUBSTITUTED BENZAMIDES AND METHODS OF USE THEREOF | GENENTECH, INC. (US) | 2015-06-04 | — | — | WO | disclosed |