Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TBXAS1 | P24557 | 9/20 | 0.72 |
| ▸ | CYP19A1 | P11511 | 6/20 | 0.60 |
| ▸ | PKM | P14618 | 1/20 | 0.55 |
| ▸ | GAA | P10253 | 1/20 | 0.54 |
| ▸ | CYP11B1 | P15538 | 2/20 | 0.51 |
| ▸ | CYP11B2 | P19099 | 2/20 | 0.51 |
| ▸ | PLA2G4A | P47712 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11354168 | 0.86 | TBXAS1 (0.74) | TBXAS1CYP19A1CYP11B1CYP11B2PLA2G4A | |
| SCHEMBL11207086 | 0.84 | TBXAS1 (0.67) | TBXAS1CYP19A1PKMGAA | |
| SCHEMBL10852178 | 0.84 | TBXAS1 (1.00) | TBXAS1CYP19A1CYP11B1CYP11B2 | |
| Hydrochloric Acid SCHEMBL10854369 | 0.83 | TBXAS1 (1.00) | TBXAS1CYP19A1 | |
| SCHEMBL10945811 | 0.83 | TBXAS1 (0.78) | TBXAS1CYP19A1CYP11B1CYP11B2 | |
| Hydrochloric Acid SCHEMBL10854125 | 0.82 | TBXAS1 (0.97) | TBXAS1CYP19A1 | |
| SCHEMBL11213142 | 0.81 | TBXAS1 (0.63) | TBXAS1CYP19A1PKM | |
| SCHEMBL10657236 | 0.81 | TBXAS1 (0.74) | TBXAS1CYP19A1CYP11B1CYP11B2PLA2G4A | |
| SCHEMBL11208084 | 0.80 | TBXAS1 (0.62) | TBXAS1CYP19A1PKM | |
| SCHEMBL11206265 | 0.79 | TBXAS1 (0.61) | TBXAS1CYP19A1PKMGAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4555516-A | FOR TREATMENT OF CARDIOVASCULAR DISORDERS | PFIZER INC. (US) | 1985-11-26 | — | — | US | disclosed |
| US-4448781-A | CARDIOVASCULAR DISORDERS | PFIZER INC. (US) | 1984-05-15 | — | — | US | disclosed |