Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TAAR1 | Q96RJ0 | 3/20 | 0.49 |
| ▸ | MAPT | P10636 | 2/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
| ▸ | PRKAB2 | O43741 | 1/20 | 0.42 |
| ▸ | PRKAG1 | P54619 | 1/20 | 0.42 |
| ▸ | PRKAA2 | P54646 | 1/20 | 0.42 |
| ▸ | PRKAA1 | Q13131 | 1/20 | 0.42 |
| ▸ | PRKAG3 | Q9UGI9 | 1/20 | 0.42 |
| ▸ | PRKAG2 | Q9UGJ0 | 1/20 | 0.42 |
| ▸ | PRKAB1 | Q9Y478 | 1/20 | 0.42 |
| ▸ | PKM | P14618 | 2/20 | 0.42 |
| ▸ | RECQL | P46063 | 1/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.41 |
| ▸ | NPC1 | O15118 | 1/20 | 0.41 |
| ▸ | ALPL | P05186 | 1/20 | 0.41 |
| ▸ | RAB9A | P51151 | 1/20 | 0.41 |
| ▸ | GAA | P10253 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11207092 | 0.85 | GAA (0.59) | TAAR1MAPTLMNAPKMSMN1; SMN2 | |
| SCHEMBL10852193 | 0.85 | TAAR1 (0.57) | TAAR1MAPTMEN1KMT2AALDH1A1 | |
| SCHEMBL10945831 | 0.83 | TAAR1 (0.51) | TAAR1MAPTPRKAB2PRKAG1PRKAA2 | |
| Hydrochloric Acid SCHEMBL10854378 | 0.83 | TAAR1 (0.55) | TAAR1MAPTMEN1KMT2AALDH1A1 | |
| SCHEMBL10852582 | 0.83 | GAA (0.51) | TAAR1MAPTALDH1A1SMN1; SMN2GAA | |
| Hydrochloric Acid SCHEMBL10854139 | 0.82 | TAAR1 (0.54) | TAAR1MAPTMEN1KMT2AALDH1A1 | |
| SCHEMBL11213148 | 0.82 | RAB9A (0.52) | TAAR1MAPTLMNAPKMMEN1 | |
| SCHEMBL11206271 | 0.81 | ALPL (0.46) | TAAR1MAPTLMNAPKMALDH1A1 | |
| SCHEMBL11208093 | 0.81 | NPC1 (0.62) | MAPTLMNAPKMMEN1KMT2A | |
| SCHEMBL11706270 | 0.78 | TAAR1 (0.59) | TAAR1MAPTLMNAALDH1A1SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4555516-A | FOR TREATMENT OF CARDIOVASCULAR DISORDERS | PFIZER INC. (US) | 1985-11-26 | — | — | US | disclosed |
| US-4448781-A | CARDIOVASCULAR DISORDERS | PFIZER INC. (US) | 1984-05-15 | — | — | US | disclosed |