Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 8/20 | 0.52 |
| ▸ | NPC1 | O15118 | 7/20 | 0.52 |
| ▸ | TP53 | P04637 | 3/20 | 0.49 |
| ▸ | PKM | P14618 | 2/20 | 0.49 |
| ▸ | GAA | P10253 | 2/20 | 0.48 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.48 |
| ▸ | MAPT | P10636 | 2/20 | 0.48 |
| ▸ | TSHR | P16473 | 2/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.48 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.48 |
| ▸ | PSMB5 | P28074 | 1/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.47 |
| ▸ | MEN1 | O00255 | 2/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.47 |
| ▸ | LMNA | P02545 | 1/20 | 0.47 |
| ▸ | MITF | O75030 | 1/20 | 0.46 |
| ▸ | HPGD | P15428 | 1/20 | 0.46 |
| ▸ | XBP1 | P17861 | 1/20 | 0.46 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.45 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11207092 | 0.87 | GAA (0.59) | RAB9ANPC1PKMGAATAAR1 | |
| SCHEMBL10947493 | 0.82 | TAAR1 (0.49) | RAB9ANPC1PKMGAATAAR1 | |
| SCHEMBL11208093 | 0.79 | NPC1 (0.62) | RAB9ANPC1TP53PKMMAPT | |
| SCHEMBL11206271 | 0.79 | ALPL (0.46) | RAB9ANPC1TP53PKMGAA | |
| SCHEMBL11407592 | 0.78 | NPC1 (0.57) | RAB9ANPC1TP53PKMGAA | |
| SCHEMBL10852193 | 0.78 | TAAR1 (0.57) | TAAR1MAPTSMN1; SMN2KMT2AMEN1 | |
| Hydrochloric Acid SCHEMBL7014888 | 0.77 | GAA (0.69) | RAB9ANPC1TP53PKMGAA | |
| SCHEMBL2562542 | 0.77 | RAB9A (0.59) | RAB9ANPC1TP53PKMGAA | |
| Hydrochloric Acid SCHEMBL10854378 | 0.76 | TAAR1 (0.55) | TAAR1MAPTSMN1; SMN2KMT2AMEN1 | |
| SCHEMBL10945831 | 0.76 | TAAR1 (0.51) | RAB9ATP53GAATAAR1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0035863-B1 | IMIDAZOLE DERIVATIVES, PROCESS FOR THEIR PREPARATION AND PHARMACEUTICAL COMPOSITIONS THEREOF | Pfizer Limited (GB) | 1983-10-26 | — | — | EP | claimed |
| US-4350696-A | INHIBITORS OF THROMBOXANE SYNTHETASE ENZYME | PFIZER INC. (US) | 1982-09-21 | — | — | US | claimed |
| EP-0035863-B1 | IMIDAZOLE DERIVATIVES, PROCESS FOR THEIR PREPARATION AND PHARMACEUTICAL COMPOSITIONS THEREOF | Pfizer Limited (GB) | 1983-10-26 | — | — | EP | disclosed |
| US-4350696-A | INHIBITORS OF THROMBOXANE SYNTHETASE ENZYME | PFIZER INC. (US) | 1982-09-21 | — | — | US | disclosed |
| EP-0035863-A1 | Imidazole derivatives, process for their preparation and pharmaceutical compositions thereof | Pfizer Limited (GB) | 1981-09-16 | — | — | EP | disclosed |