Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALPL | P05186 | 6/20 | 0.46 |
| ▸ | NPC1 | O15118 | 3/20 | 0.46 |
| ▸ | RAB9A | P51151 | 3/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.46 |
| ▸ | PKM | P14618 | 1/20 | 0.46 |
| ▸ | MAPT | P10636 | 3/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | TP53 | P04637 | 1/20 | 0.39 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.38 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.38 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.38 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.38 |
| ▸ | ALPI | P09923 | 1/20 | 0.38 |
| ▸ | ALPG | P10696 | 1/20 | 0.38 |
| ▸ | P2RY14 | Q15391 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11207092 | 0.81 | GAA (0.59) | ALPLNPC1RAB9ASMN1; SMN2PKM | |
| SCHEMBL10947493 | 0.81 | TAAR1 (0.49) | ALPLNPC1RAB9ASMN1; SMN2PKM | |
| SCHEMBL11213148 | 0.79 | RAB9A (0.52) | NPC1RAB9ASMN1; SMN2PKMMAPT | |
| SCHEMBL11208093 | 0.78 | NPC1 (0.62) | NPC1RAB9ASMN1; SMN2PKMMAPT | |
| SCHEMBL10852193 | 0.77 | TAAR1 (0.57) | SMN1; SMN2MAPTTAAR1ALDH1A1 | |
| Hydrochloric Acid SCHEMBL10854378 | 0.76 | TAAR1 (0.55) | SMN1; SMN2MAPTTAAR1ALDH1A1 | |
| SCHEMBL10945831 | 0.76 | TAAR1 (0.51) | RAB9ASMN1; SMN2MAPTTAAR1ALDH1A1 | |
| Hydrochloric Acid SCHEMBL10854139 | 0.74 | TAAR1 (0.54) | SMN1; SMN2MAPTTAAR1ALDH1A1 | |
| SCHEMBL11206265 | 0.74 | TBXAS1 (0.61) | ALPLNPC1RAB9ASMN1; SMN2PKM | |
| SCHEMBL11407592 | 0.73 | NPC1 (0.57) | NPC1RAB9ASMN1; SMN2PKMMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0035863-B1 | IMIDAZOLE DERIVATIVES, PROCESS FOR THEIR PREPARATION AND PHARMACEUTICAL COMPOSITIONS THEREOF | Pfizer Limited (GB) | 1983-10-26 | — | — | EP | claimed |
| US-4350696-A | INHIBITORS OF THROMBOXANE SYNTHETASE ENZYME | PFIZER INC. (US) | 1982-09-21 | — | — | US | claimed |
| EP-0035863-A1 | Imidazole derivatives, process for their preparation and pharmaceutical compositions thereof | Pfizer Limited (GB) | 1981-09-16 | — | — | EP | claimed |