Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RXRB | P28702 | 8/20 | 0.40 |
| ▸ | RXRA | P19793 | 7/20 | 0.40 |
| ▸ | RXRG | P48443 | 6/20 | 0.40 |
| ▸ | MRGPRX4 | Q96LA9 | 2/20 | 0.39 |
| ▸ | PARP10 | Q53GL7 | 1/20 | 0.39 |
| ▸ | PTGER1 | P34995 | 3/20 | 0.38 |
| ▸ | PPARG | P37231 | 1/20 | 0.38 |
| ▸ | PPARD | Q03181 | 1/20 | 0.38 |
| ▸ | BRD4 | O60885 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.37 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.37 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.37 |
| ▸ | POLB | P06746 | 1/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10948152 | 1.00 | RXRB (0.40) | RXRBRXRARXRGMRGPRX4PARP10 | |
| SCHEMBL10880896 | 0.87 | RXRA (0.41) | RXRBRXRARXRGMRGPRX4PPARG | |
| SCHEMBL10880892 | 0.87 | RXRA (0.41) | RXRBRXRARXRGMRGPRX4PPARG | |
| SCHEMBL10951400 | 0.85 | MRGPRX4 (0.55) | RXRBRXRARXRGMRGPRX4PTGER1 | |
| SCHEMBL11726269 | 0.81 | RAB9A (0.47) | RXRBRXRARXRGMRGPRX4PTGER1 | |
| SCHEMBL11720690 | 0.81 | RAB9A (0.47) | RXRBRXRARXRGMRGPRX4PTGER1 | |
| SCHEMBL10955123 | 0.80 | ALDH1A1 (0.51) | RXRBRXRARXRGPTGER1ALDH1A1 | |
| SCHEMBL10955119 | 0.80 | ALDH1A1 (0.51) | RXRBRXRARXRGPTGER1ALDH1A1 | |
| SCHEMBL11725755 | 0.78 | RAB9A (0.44) | RXRBRXRARXRGMRGPRX4BRD4 | |
| SCHEMBL11721103 | 0.78 | NPC1 (0.39) | RXRBRXRARXRGMRGPRX4BRD4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4559361-A | INTRAOCULAR PRESSURE DEPRESSANTS, TREATMENT OF GLAUCOMA | SENJU PHARMACEUTICAL CO., LTD. (JP) | 1985-12-17 | — | — | US | disclosed |