Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 7/20 | 0.68 |
| ▸ | MEN1 | O00255 | 6/20 | 0.68 |
| ▸ | KMT2A | Q03164 | 6/20 | 0.68 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.68 |
| ▸ | HSPB1 | P04792 | 4/20 | 0.68 |
| ▸ | POLB | P06746 | 2/20 | 0.60 |
| ▸ | LMNA | P02545 | 6/20 | 0.53 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.53 |
| ▸ | HTT | P42858 | 3/20 | 0.53 |
| ▸ | GLA | P06280 | 2/20 | 0.53 |
| ▸ | GAA | P10253 | 2/20 | 0.53 |
| ▸ | HPGD | P15428 | 2/20 | 0.53 |
| ▸ | THRB | P10828 | 1/20 | 0.52 |
| ▸ | TTR | P02766 | 3/20 | 0.48 |
| ▸ | PDE7A | Q13946 | 2/20 | 0.48 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11322040 | 0.86 | MEN1 (0.82) | MAPTMEN1KMT2AALDH1A1HSPB1 | |
| SCHEMBL11326830 | 0.85 | ALDH1A1 (0.63) | MAPTMEN1KMT2AALDH1A1HSPB1 | |
| SCHEMBL21652814 | 0.84 | MEN1 (0.48) | MAPTMEN1KMT2AALDH1A1HSPB1 | |
| SCHEMBL5315876 | 0.84 | MAPT (0.73) | MAPTMEN1KMT2AALDH1A1HSPB1 | |
| SCHEMBL25518736 | 0.84 | ALDH1A1 (0.73) | MAPTMEN1KMT2AALDH1A1HSPB1 | |
| SCHEMBL27720337 | 0.83 | MAPT (0.77) | MAPTMEN1KMT2AALDH1A1HSPB1 | |
| SCHEMBL28589234 | 0.82 | MAPT (0.75) | MAPTMEN1KMT2AALDH1A1HSPB1 | |
| SCHEMBL27713527 | 0.81 | ALDH1A1 (0.73) | MAPTMEN1KMT2AALDH1A1HSPB1 | |
| SCHEMBL620493 | 0.81 | HSPB1 (0.59) | MAPTMEN1KMT2AALDH1A1HSPB1 | |
| SCHEMBL6153036 | 0.81 | VCAM1 (0.47) | MAPTMEN1KMT2AALDH1A1HSPB1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4505929-A | Sulfur-substituted diphenyl ethers having antiviral activity | THE DOW CHEMICAL COMPANY (US) | 1985-03-19 | — | — | US | disclosed |
| US-4349568-A | Sulfur-substituted diphenyl ethers having antiviral activity | THE DOW CHEMICAL COMPANY (US) | 1982-09-14 | — | — | US | disclosed |