Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA2 | P00918 | 8/20 | 0.64 |
| ▸ | CA1 | P00915 | 6/20 | 0.64 |
| ▸ | CA9 | Q16790 | 4/20 | 0.64 |
| ▸ | CA4 | P22748 | 1/20 | 0.64 |
| ▸ | CA7 | P43166 | 3/20 | 0.56 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.48 |
| ▸ | CA12 | O43570 | 2/20 | 0.48 |
| ▸ | TSHR | P16473 | 1/20 | 0.48 |
| ▸ | PLAU | P00749 | 1/20 | 0.47 |
| ▸ | HPN | P05981 | 1/20 | 0.47 |
| ▸ | MMP2 | P08253 | 4/20 | 0.46 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.46 |
| ▸ | AIMP2 | Q13155 | 1/20 | 0.46 |
| ▸ | MEN1 | O00255 | 1/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.46 |
| ▸ | MMP1 | P03956 | 3/20 | 0.44 |
| ▸ | MMP9 | P14780 | 3/20 | 0.44 |
| ▸ | MMP13 | P45452 | 3/20 | 0.44 |
| ▸ | MMP3 | P08254 | 2/20 | 0.44 |
| ▸ | MMP7 | P09237 | 2/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8201579 | 0.78 | CA2 (0.69) | CA2CA1CA9CA4CA7 | |
| SCHEMBL10779550 | 0.77 | CA2 (0.63) | CA2CA1CA9CA4CA7 | |
| SCHEMBL10779555 | 0.77 | CA2 (0.63) | CA2CA1CA9CA4CA7 | |
| SCHEMBL10779543 | 0.77 | CA2 (0.63) | CA2CA1CA9CA4CA7 | |
| SCHEMBL21538642 | 0.76 | CA2 (0.68) | CA2CA1CA9CA4CA7 | |
| SCHEMBL12406332 | 0.74 | CA2 (0.58) | CA2CA1CA9CA4CA7 | |
| SCHEMBL28625510 | 0.73 | ALDH1A1 (0.71) | CA2CA1CA9CA4CA7 | |
| SCHEMBL11351046 | 0.72 | MMP9 (0.71) | CA2CA1CA9CA4CA7 | |
| SCHEMBL7434664 | 0.72 | AIMP2 (0.60) | CA2CA1CA9CA4CA7 | |
| SCHEMBL7066619 | 0.72 | MMP9 (0.71) | CA2CA1CA9CA4CA7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4555506-A | Phosphorus containing compounds and use as hypotensives | E. R. SQUIBB & SONS, INC. (US) | 1985-11-26 | — | — | US | disclosed |