Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PSMB8 | P28062 | 1/20 | 0.32 |
| ▸ | PSMB5 | P28074 | 1/20 | 0.32 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4080660 | 0.93 | PSMB8 (0.34) | PSMB8PSMB5 | |
| SCHEMBL1095836 | 0.91 | — | — | |
| SCHEMBL13770053 | 0.91 | PSMB8 (0.33) | PSMB8PSMB5HDAC6 | |
| SCHEMBL1095524 | 0.90 | HDAC6 (0.33) | HDAC6 | |
| SCHEMBL1095835 | 0.90 | — | — | |
| SCHEMBL1095810 | 0.85 | PSMB8 (0.32) | PSMB8PSMB5 | |
| SCHEMBL14078003 | 0.85 | ABCB1 (0.34) | PSMB8PSMB5 | |
| SCHEMBL14078004 | 0.85 | KDM4E (0.31) | HDAC6 | |
| SCHEMBL18258300 | 0.85 | KDM4E (0.34) | HDAC6 | |
| SCHEMBL22247631 | 0.85 | FTO (0.33) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8153827-B2 | Reagents for biomolecular labeling, detection and quantification employing Raman spectroscopy | PURDUE RESEARCH FOUNDATION (US) | 2012-04-10 | — | — | US | disclosed |
| US-20090219526-A1 | REAGENTS FOR BIOMOLECULAR LABELING, DETECTION AND QUANTIFICATION EMPLOYING RAMAN SPECTROSCOPY | NATIONAL INSTITUTES OF HEALTH (NIH), U.S. DEPT. OF HEALTH AND HUMAN SERVICES (DHHS), U.S. GOVERNMENT | 2009-09-03 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090219526-A1 | REAGENTS FOR BIOMOLECULAR LABELING, DETECTION AND QUANTIFICATION EMPLOYING RAMAN SPECTROSCOPY | SRMS, UQCRB, UQCRC1 | PSMB8 2581/4885PSMB5 2099/4885HDAC6 3345/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.