Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.32 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL205104 | 0.79 | PTGS1 (0.38) | — | |
| SCHEMBL2696112 | 0.78 | TSHR (0.61) | TSHRMEN1CYP3A4ALOX15KMT2A | |
| SCHEMBL8380926 | 0.77 | ALDH1A1 (0.39) | TSHRLMNA | |
| SCHEMBL8377668 | 0.76 | LMNA (0.43) | TSHRMEN1CYP3A4KMT2ALMNA | |
| SCHEMBL14978790 | 0.76 | LMNA (0.43) | TSHRMEN1CYP3A4KMT2ALMNA | |
| SCHEMBL26656748 | 0.75 | TSHR (0.58) | TSHRMEN1CYP3A4ALOX15KMT2A | |
| SCHEMBL274264 | 0.74 | DPP4 (0.38) | ALOX15 | |
| SCHEMBL8368987 | 0.73 | — | — | |
| SCHEMBL541637 | 0.72 | TSHR (0.61) | TSHRCYP3A4LMNA | |
| SCHEMBL28072185 | 0.72 | TSHR (0.35) | TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4500494-A | POLYUREA OR UREA-FORMALDEHYDE SHELLS CONTAINING DIKETONE, 8-HYDROXYQUINOLINE OR OXIME | STAUFFER CHEMICAL COMPANY (US) | 1985-02-19 | — | — | US | disclosed |