SCHEMBL8380926

SCHEMBL8380926

CCCCC(C)C(C)(C)CO

nearest known ligand 0.39

Predicted protein targets (top 10)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 2/20 0.39
CA2 P00918 7/20 0.37
MAPK1 P28482 1/20 0.37
CA1 P00915 4/20 0.35
LMNA P02545 1/20 0.34
TSHR P16473 2/20 0.33
DNM1 Q05193 2/20 0.33
SMN1; SMN2 Q16637 2/20 0.33
FDPS P14324 1/20 0.33
OPRM1 P35372 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL14978790 0.93 LMNA (0.43) ALDH1A1CA2CA1LMNATSHR
SCHEMBL8377668 0.93 LMNA (0.43) ALDH1A1CA2CA1LMNATSHR
SCHEMBL1027361 0.85 TSHR (0.42) ALDH1A1LMNATSHR
SCHEMBL205104 0.83 PTGS1 (0.38)
SCHEMBL7756753 0.80 DNM1 (0.36) ALDH1A1CA2MAPK1CA1TSHR
SCHEMBL21989957 0.78 DNM1 (0.35) ALDH1A1CA2MAPK1CA1TSHR
SCHEMBL7798243 0.78 ALDH1A1 (0.41) ALDH1A1CA2MAPK1CA1LMNA
SCHEMBL10955729 0.77 TSHR (0.41) LMNATSHR
SCHEMBL274264 0.77 DPP4 (0.38) ALDH1A1
SCHEMBL1970000 0.76 DNM1 (0.33) ALDH1A1CA2MAPK1CA1TSHR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0376997-B2 THERMAL OXIDATIVELY STABLE SYNTHETIC FLUID COMPOSITION LUBRIZOL CORP (US) 1999-03-31 EP disclosed
EP-0376997-B1 THERMAL OXIDATIVELY STABLE SYNTHETIC FLUID COMPOSITION LUBRIZOL CORP (US) 1995-01-18 EP disclosed
EP-0340250-B1 SPIN FIBER LUBRICANT COMPOSITIONS LUBRIZOL CORP (US) 1994-10-05 EP disclosed
US-5164122-A Oil additive THE LUBRIZOL CORPORATION (US) 1992-11-17 US disclosed
US-4957648-A Neoalcohol esters; antistatic agents for yarns THE LUBRIZOL CORPORATION (US) 1990-09-18 US disclosed
EP-0376997-A1 THERMAL OXIDATIVELY STABLE SYNTHETIC FLUID COMPOSITION. LUBRIZOL CORP (US) 1990-07-11 EP disclosed
EP-0340250-A1 SPIN FIBER LUBRICANT COMPOSITIONS The Lubrizol Corporation (US) 1989-11-08 EP disclosed
WO-1989010345-A1 THERMAL OXIDATIVELY STABLE SYNTHETIC FLUID COMPOSITION THE LUBRIZOL CORPORATION (US) 1989-11-02 WO disclosed
WO-1989009812-A1 LUBRICATING OIL ADDITIVES THE LUBRIZOL CORPORATION (US) 1989-10-19 WO disclosed
WO-1989001071-A1 SPIN FIBER LUBRICANT COMPOSITIONS THE LUBRIZOL CORPORATION (US) 1989-02-09 WO disclosed