Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 4/20 | 0.43 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.41 |
| ▸ | CA1 | P00915 | 2/20 | 0.39 |
| ▸ | SPHK1 | Q9NYA1 | 2/20 | 0.39 |
| ▸ | TP53 | P04637 | 2/20 | 0.38 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.36 |
| ▸ | GMNN | O75496 | 1/20 | 0.36 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
| ▸ | THPO | P40225 | 1/20 | 0.36 |
| ▸ | MTOR | P42345 | 1/20 | 0.36 |
| ▸ | BLM | P54132 | 1/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.36 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | CETP | P11597 | 1/20 | 0.36 |
| ▸ | HTT | P42858 | 1/20 | 0.36 |
| ▸ | UBE2N | P61088 | 1/20 | 0.36 |
| ▸ | CA2 | P00918 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14978790 | 1.00 | LMNA (0.43) | LMNAOPRM1CA1SPHK1TP53 | |
| SCHEMBL8380926 | 0.93 | ALDH1A1 (0.39) | LMNAOPRM1CA1CA2SMN1; SMN2 | |
| SCHEMBL1027361 | 0.83 | TSHR (0.42) | LMNAALDH1A1TSHR | |
| SCHEMBL205104 | 0.81 | PTGS1 (0.38) | — | |
| SCHEMBL20609980 | 0.81 | OPRM1 (0.44) | LMNAOPRM1CA1SPHK1TP53 | |
| SCHEMBL29209888 | 0.79 | OPRM1 (0.42) | LMNAOPRM1SPHK1CA2ACE2 | |
| SCHEMBL28880009 | 0.79 | OPRM1 (0.42) | LMNAOPRM1CA1SPHK1TP53 | |
| SCHEMBL2761465 | 0.79 | OPRM1 (0.42) | LMNAOPRM1SPHK1CA2ACE2 | |
| SCHEMBL13060029 | 0.77 | OPRM1 (0.46) | OPRM1CA1SPHK1TP53ALDH1A1 | |
| SCHEMBL1973151 | 0.77 | OPRM1 (0.41) | LMNAOPRM1CA1SPHK1TP53 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0376997-B2 | THERMAL OXIDATIVELY STABLE SYNTHETIC FLUID COMPOSITION | LUBRIZOL CORP (US) | 1999-03-31 | — | — | EP | disclosed |
| EP-0376997-B1 | THERMAL OXIDATIVELY STABLE SYNTHETIC FLUID COMPOSITION | LUBRIZOL CORP (US) | 1995-01-18 | — | — | EP | disclosed |
| EP-0340250-B1 | SPIN FIBER LUBRICANT COMPOSITIONS | LUBRIZOL CORP (US) | 1994-10-05 | — | — | EP | disclosed |
| US-5164122-A | Oil additive | THE LUBRIZOL CORPORATION (US) | 1992-11-17 | — | — | US | disclosed |
| US-4957648-A | Neoalcohol esters; antistatic agents for yarns | THE LUBRIZOL CORPORATION (US) | 1990-09-18 | — | — | US | disclosed |
| EP-0376997-A1 | THERMAL OXIDATIVELY STABLE SYNTHETIC FLUID COMPOSITION. | LUBRIZOL CORP (US) | 1990-07-11 | — | — | EP | disclosed |
| EP-0340250-A1 | SPIN FIBER LUBRICANT COMPOSITIONS | The Lubrizol Corporation (US) | 1989-11-08 | — | — | EP | disclosed |
| WO-1989010345-A1 | THERMAL OXIDATIVELY STABLE SYNTHETIC FLUID COMPOSITION | THE LUBRIZOL CORPORATION (US) | 1989-11-02 | — | — | WO | disclosed |
| WO-1989009812-A1 | LUBRICATING OIL ADDITIVES | THE LUBRIZOL CORPORATION (US) | 1989-10-19 | — | — | WO | disclosed |
| WO-1989001071-A1 | SPIN FIBER LUBRICANT COMPOSITIONS | THE LUBRIZOL CORPORATION (US) | 1989-02-09 | — | — | WO | disclosed |