2-Chlorophenol

2-Chlorophenol

SCHEMBL10956367

OCc1cccc(CO)c1O.Oc1ccccc1Cl

nearest known ligand 0.60

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 2/20 0.60
TSHR P16473 3/20 0.45
HSPA5 P11021 1/20 0.41
HSP90AA1 P07900 1/20 0.41
GABRA1 P14867 1/20 0.40
GABRB2 P47870 1/20 0.40
TTR P02766 1/20 0.40
PNMT P11086 2/20 0.39
IDO1 P14902 1/20 0.39
LMNA P02545 2/20 0.38
KDM4E B2RXH2 1/20 0.38
TP53 P04637 1/20 0.38
MAPT P10636 1/20 0.38
ALOX12 P18054 1/20 0.38
CYP2D6 P10635 1/20 0.38
HIF1A Q16665 1/20 0.38
AR P10275 1/20 0.38
APOBEC3G Q9HC16 1/20 0.38
SHBG P04278 1/20 0.37
PKM P14618 1/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5710254 0.83 HSP90AA1 (0.55) ALDH1A1TSHRHSP90AA1GABRA1GABRB2
SCHEMBL196227 0.80 GABRA1 (0.57) ALDH1A1TSHRHSPA5GABRA1GABRB2
SCHEMBL66634 0.78 LMNA (0.55) ALDH1A1TSHRHSPA5GABRA1GABRB2
SCHEMBL11686142 0.78 HSPA5 (0.67) TSHRHSPA5GABRA1GABRB2IDO1
2-Chlorophenol SCHEMBL8961529 0.78 ALDH1A1 (1.00) ALDH1A1TSHRHSPA5LMNAKDM4E
2-Chlorophenol SCHEMBL12279 0.78
2-Chlorophenol SCHEMBL29354452 0.78
2-Chlorophenol SCHEMBL28504762 0.76 ALDH1A1 (0.75) ALDH1A1TSHRHSPA5HSP90AA1LMNA
SCHEMBL96359 0.75
2-Chlorophenol SCHEMBL10882437 0.75 ALDH1A1 (0.94) ALDH1A1TSHRHSPA5LMNAKDM4E

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-4614826-A CURABLE TO EPOXY RESINS; HEAT RESISTANCE MITSUI PETROCHEMICAL INDUSTRIES, LTD. (JP) 1986-09-30 US disclosed