Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FGFR1 | P11362 | 2/20 | 0.44 |
| ▸ | FGFR2 | P21802 | 2/20 | 0.44 |
| ▸ | FGFR4 | P22455 | 2/20 | 0.44 |
| ▸ | FGFR3 | P22607 | 2/20 | 0.44 |
| ▸ | SRC | P12931 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.43 |
| ▸ | HPGD | P15428 | 3/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.43 |
| ▸ | NPC1 | O15118 | 2/20 | 0.43 |
| ▸ | RAB9A | P51151 | 2/20 | 0.43 |
| ▸ | MEN1 | O00255 | 2/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.43 |
| ▸ | MAPT | P10636 | 2/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.43 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.42 |
| ▸ | TSHR | P16473 | 3/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
| ▸ | CA12 | O43570 | 1/20 | 0.40 |
| ▸ | CA1 | P00915 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11099181 | 0.85 | ALDH1A1 (0.52) | FGFR1FGFR2FGFR4FGFR3SRC | |
| SCHEMBL11821428 | 0.82 | MAOA (0.43) | ALDH1A1KDM4ENPC1RAB9AMEN1 | |
| SCHEMBL28800092 | 0.81 | FGFR1 (0.46) | FGFR1FGFR2FGFR4FGFR3SRC | |
| SCHEMBL6654078 | 0.78 | ALDH1A1 (0.52) | FGFR1FGFR2FGFR4FGFR3SRC | |
| SCHEMBL10956402 | 0.77 | SRD5A2 (0.41) | ALDH1A1KDM4EHPGDNPC1RAB9A | |
| SCHEMBL1821797 | 0.76 | FGFR1 (0.39) | FGFR1FGFR2FGFR4FGFR3SRC | |
| SCHEMBL20444060 | 0.76 | HSD11B1 (0.50) | ALDH1A1KDM4EHPGDL3MBTL1NPC1 | |
| SCHEMBL12401719 | 0.76 | KDM4E (0.47) | ALDH1A1KDM4EHPGDL3MBTL1NPC1 | |
| SCHEMBL18294846 | 0.75 | LOXL2 (0.44) | ALDH1A1KDM4EHPGDL3MBTL1RAB9A | |
| Fluorene SCHEMBL2708609 | 0.74 | TSHR (0.68) | ALDH1A1KDM4EHPGDL3MBTL1NPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0976709-A1 | 2,3-DISUBSTITUTED CYCLOPENTANONE DERIVATIVES, PROCESS FOR PRODUCING THE SAME, AND MEDICINAL USE THEREOF | NIPPON KAYAKU CO., LTD. (JP) | 2000-02-02 | — | — | EP | disclosed |