Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 6/20 | 0.40 |
| ▸ | MAPT | P10636 | 4/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.40 |
| ▸ | GAA | P10253 | 1/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 5/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
| ▸ | TSHR | P16473 | 1/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.40 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.39 |
| ▸ | DRD2 | P14416 | 1/20 | 0.39 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.39 |
| ▸ | DRD3 | P35462 | 1/20 | 0.39 |
| ▸ | ADRA1B | P35368 | 2/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.38 |
| ▸ | HPGD | P15428 | 2/20 | 0.37 |
| ▸ | TP53 | P04637 | 2/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10750346 | 0.88 | ADRA2A (0.42) | KDM4EMAPTKMT2AHSD17B10SMN1; SMN2 | |
| SCHEMBL10767817 | 0.81 | ALDH1A1 (0.43) | KDM4EMAPTKMT2AHSD17B10SMN1; SMN2 | |
| SCHEMBL10957936 | 0.79 | CYP1A2 (0.47) | KDM4EMAPTKMT2AHSD17B10SMN1; SMN2 | |
| SCHEMBL10958050 | 0.77 | ADRA2A (0.39) | KDM4EMAPTKMT2AHSD17B10SMN1; SMN2 | |
| SCHEMBL10956542 | 0.75 | ALDH1A1 (0.53) | KDM4EMAPTKMT2AHSD17B10SMN1; SMN2 | |
| SCHEMBL10957578 | 0.75 | ADORA3 (0.42) | KDM4EHSD17B10SMN1; SMN2ALDH1A1HPGD | |
| SCHEMBL10769001 | 0.72 | ADRA2A (0.74) | KDM4EKMT2AHSD17B10ADRA2ADRD2 | |
| Bromide SCHEMBL10771783 | 0.71 | ADRA2A (0.73) | KDM4EKMT2AHSD17B10ADRA2ADRD2 | |
| SCHEMBL10750340 | 0.69 | PDE3B (0.39) | KDM4EMAPTHSD17B10SMN1; SMN2ALDH1A1 | |
| SCHEMBL17517369 | 0.69 | TRPC5 (0.67) | KDM4EMAPTKMT2AHSD17B10L3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0176333-A2 | Substituted quinazolinediones | ORTHO PHARMACEUTICAL CORPORATION (US) | 1986-04-02 | — | — | EP | disclosed |