Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSD11B1 | P28845 | 1/20 | 0.64 |
| ▸ | PTGS1 | P23219 | 3/20 | 0.57 |
| ▸ | PTGS2 | P35354 | 3/20 | 0.57 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.57 |
| ▸ | USP2 | O75604 | 2/20 | 0.57 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.57 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.57 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.57 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.57 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.57 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.57 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.57 |
| ▸ | BLM | P54132 | 1/20 | 0.57 |
| ▸ | SLC22A6 | Q4U2R8 | 1/20 | 0.57 |
| ▸ | SLC22A8 | Q8TCC7 | 1/20 | 0.57 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.56 |
| ▸ | LMNA | P02545 | 1/20 | 0.54 |
| ▸ | KDR | P35968 | 1/20 | 0.54 |
| ▸ | PTGES | O14684 | 1/20 | 0.54 |
| ▸ | ABCB11 | O95342 | 1/20 | 0.53 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Ammonia Solution, Strong SCHEMBL10369736 | 0.86 | HSD11B1 (0.63) | HSD11B1PTGS1PTGS2KDM4EUSP2 | |
| SCHEMBL3495355 | 0.86 | HSD11B1 (0.66) | HSD11B1PTGS1PTGS2KDM4EUSP2 | |
| SCHEMBL2351157 | 0.86 | HSD11B1 (0.66) | HSD11B1PTGS1PTGS2KDM4EUSP2 | |
| SCHEMBL10959470 | 0.85 | PTGS1 (0.65) | HSD11B1PTGS1PTGS2KDM4EUSP2 | |
| SCHEMBL7995819 | 0.84 | HSD11B1 (0.64) | HSD11B1PTGS1PTGS2KDM4EUSP2 | |
| SCHEMBL11493483 | 0.82 | CAPN1 (0.54) | HSD11B1PTGS1PTGS2KDM4EUSP2 | |
| SCHEMBL30218271 | 0.82 | HSD11B1 (0.73) | HSD11B1PTGS1PTGS2KDM4EUSP2 | |
| SCHEMBL6796426 | 0.82 | HSD11B1 (0.73) | HSD11B1PTGS1PTGS2KDM4EUSP2 | |
| SCHEMBL30218275 | 0.81 | PTGS1 (0.64) | HSD11B1PTGS1PTGS2KDM4EUSP2 | |
| SCHEMBL10369737 | 0.81 | PTGS1 (0.64) | HSD11B1PTGS1PTGS2KDM4EUSP2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4533664-A | Antithrombotic N-(6-chloro-pyrazin-2-yl)-4-Hydroxy-2H-1,2-benzothiazine-3-carboxamide-1,1-dioxide derivatives, composition, and method of use | DR. KARL THOMAE GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DE) | 1985-08-06 | — | — | US | disclosed |
| US-4233299-A | ANTIINFLAMMATORY AGENTS, ANTIPYRETICS | BOEHRINGER INGELHEIM GMBH (DE) | 1980-11-11 | — | — | US | disclosed |