Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSD11B1 | P28845 | 1/20 | 0.73 |
| ▸ | PTGS1 | P23219 | 3/20 | 0.58 |
| ▸ | PTGS2 | P35354 | 3/20 | 0.58 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.58 |
| ▸ | USP2 | O75604 | 2/20 | 0.58 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.58 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.58 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.58 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.58 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.58 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.58 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.58 |
| ▸ | BLM | P54132 | 1/20 | 0.58 |
| ▸ | SLC22A6 | Q4U2R8 | 1/20 | 0.58 |
| ▸ | SLC22A8 | Q8TCC7 | 1/20 | 0.58 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.57 |
| ▸ | LMNA | P02545 | 1/20 | 0.55 |
| ▸ | KDR | P35968 | 1/20 | 0.55 |
| ▸ | ABCB11 | O95342 | 1/20 | 0.54 |
| ▸ | GLA | P06280 | 1/20 | 0.54 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6796426 | 1.00 | HSD11B1 (0.73) | HSD11B1PTGS1PTGS2KDM4EUSP2 | |
| SCHEMBL6794794 | 0.85 | CAPN1 (0.57) | HSD11B1PTGS1PTGS2KDM4EUSP2 | |
| SCHEMBL3419653 | 0.85 | HSD11B1 (0.68) | HSD11B1PTGS1PTGS2KDM4EUSP2 | |
| SCHEMBL30822800 | 0.85 | HSD11B1 (1.00) | HSD11B1PTGS1PTGS2KDM4EUSP2 | |
| SCHEMBL2345581 | 0.85 | HSD11B1 (1.00) | HSD11B1PTGS1PTGS2KDM4EUSP2 | |
| SCHEMBL10964170 | 0.84 | HSD11B1 (0.75) | HSD11B1PTGS1PTGS2KDM4EUSP2 | |
| SCHEMBL2351157 | 0.83 | HSD11B1 (0.66) | HSD11B1PTGS1PTGS2KDM4EUSP2 | |
| SCHEMBL3495355 | 0.83 | HSD11B1 (0.66) | HSD11B1PTGS1PTGS2KDM4EUSP2 | |
| SCHEMBL10508168 | 0.82 | HSD11B1 (0.77) | HSD11B1PTGS1PTGS2KDM4EUSP2 | |
| SCHEMBL10957238 | 0.82 | HSD11B1 (0.58) | HSD11B1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-119371373-B | 1, 2-Benzothiazine schiff base derivative and preparation method thereof | 齐鲁医药学院 | 2025-03-04 | — | — | CN | claimed |
| CN-119371373-A | 1, 2-Benzothiazine schiff base derivative and preparation method thereof | 齐鲁医药学院 | 2025-01-28 | — | — | CN | claimed |
| CN-113527282-B | 1, 2-benzothiazine heterocyclic derivative and preparation method and application thereof | 齐鲁医药学院 | 2023-02-07 | — | — | CN | claimed |
| CN-119371373-B | 1, 2-Benzothiazine schiff base derivative and preparation method thereof | 齐鲁医药学院 | 2025-03-04 | — | — | CN | disclosed |
| CN-119371373-B | 1, 2-Benzothiazine schiff base derivative and preparation method thereof | 齐鲁医药学院 | 2025-03-04 | — | — | CN | disclosed |
| CN-119371373-A | 1, 2-Benzothiazine schiff base derivative and preparation method thereof | 齐鲁医药学院 | 2025-01-28 | — | — | CN | disclosed |
| CN-119371373-A | 1, 2-Benzothiazine schiff base derivative and preparation method thereof | 齐鲁医药学院 | 2025-01-28 | — | — | CN | disclosed |
| CN-118146065-B | Deuterated methyl iodide as well as preparation method and application thereof | 安徽实特医药科技有限公司 | 2024-07-19 | — | — | CN | disclosed |
| CN-118146065-A | Deuterated methyl iodide as well as preparation method and application thereof | 安徽实特医药科技有限公司 | 2024-06-07 | — | — | CN | disclosed |
| CN-113527282-B | 1, 2-benzothiazine heterocyclic derivative and preparation method and application thereof | 齐鲁医药学院 | 2023-02-07 | — | — | CN | disclosed |