Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSD11B1 | P28845 | 1/20 | 0.66 |
| ▸ | PTGS1 | P23219 | 3/20 | 0.59 |
| ▸ | PTGS2 | P35354 | 3/20 | 0.59 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.59 |
| ▸ | USP2 | O75604 | 2/20 | 0.59 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.59 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.59 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.59 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.59 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.59 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.59 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.59 |
| ▸ | BLM | P54132 | 1/20 | 0.59 |
| ▸ | SLC22A6 | Q4U2R8 | 1/20 | 0.59 |
| ▸ | SLC22A8 | Q8TCC7 | 1/20 | 0.59 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.57 |
| ▸ | LMNA | P02545 | 1/20 | 0.55 |
| ▸ | KDR | P35968 | 1/20 | 0.55 |
| ▸ | ABCB11 | O95342 | 1/20 | 0.54 |
| ▸ | GLA | P06280 | 1/20 | 0.54 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2351157 | 0.87 | HSD11B1 (0.66) | HSD11B1PTGS1PTGS2KDM4EUSP2 | |
| SCHEMBL7995819 | 0.86 | HSD11B1 (0.64) | HSD11B1PTGS1PTGS2KDM4EUSP2 | |
| SCHEMBL10958729 | 0.86 | HSD11B1 (0.64) | HSD11B1PTGS1PTGS2KDM4EUSP2 | |
| Ammonia Solution, Strong SCHEMBL10369736 | 0.84 | HSD11B1 (0.63) | HSD11B1PTGS1PTGS2KDM4EUSP2 | |
| SCHEMBL10959470 | 0.83 | PTGS1 (0.65) | HSD11B1PTGS1PTGS2KDM4EUSP2 | |
| SCHEMBL30218271 | 0.83 | HSD11B1 (0.73) | HSD11B1PTGS1PTGS2KDM4EUSP2 | |
| SCHEMBL6796426 | 0.83 | HSD11B1 (0.73) | HSD11B1PTGS1PTGS2KDM4EUSP2 | |
| SCHEMBL9983452 | 0.82 | HSD11B1 (0.54) | HSD11B1PTGS1PTGS2KDM4EUSP2 | |
| SCHEMBL30218275 | 0.82 | PTGS1 (0.64) | HSD11B1PTGS1PTGS2KDM4EUSP2 | |
| SCHEMBL10369737 | 0.82 | PTGS1 (0.64) | HSD11B1PTGS1PTGS2KDM4EUSP2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20100081652-A1 | Cinnamoyl Compound and Use Thereof | SHIRAKI HIROAKI | 2010-04-01 | — | — | US | disclosed |
| US-20090143368-A1 | Use of Cinnamoyl Compound | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2009-06-04 | — | — | US | disclosed |
| EP-1857455-A1 | CINNAMOYL COMPOUND AND USE THEREOF | Sumitomo Chemical Company, Limited (JP) | 2007-11-21 | — | — | EP | disclosed |
| EP-1857104-A1 | USE OF CINNAMOYL COMPOUND | Sumitomo Chemical Company, Limited (JP) | 2007-11-21 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100081652-A1 | Cinnamoyl Compound and Use Thereof | COL2A1, MMP7, COL14A1 | HSD11B1 2320/4885PTGS1 691/4885PTGS2 912/4885 |
| US-20090143368-A1 | Use of Cinnamoyl Compound | COL2A1, COL1A1, SMAD2 | HSD11B1 1016/4885PTGS1 268/4885PTGS2 465/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.