Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 4/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.40 |
| ▸ | ABL1 | P00519 | 3/20 | 0.38 |
| ▸ | GAA | P10253 | 2/20 | 0.37 |
| ▸ | NPC1 | O15118 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.37 |
| ▸ | GLA | P06280 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 1/20 | 0.37 |
| ▸ | CASP3 | P42574 | 1/20 | 0.37 |
| ▸ | RECQL | P46063 | 1/20 | 0.37 |
| ▸ | RAB9A | P51151 | 1/20 | 0.37 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.37 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.37 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.37 |
| ▸ | G6PD | P11413 | 1/20 | 0.36 |
| ▸ | ATM | Q13315 | 3/20 | 0.36 |
| ▸ | HPGD | P15428 | 1/20 | 0.36 |
| ▸ | LOX | P28300 | 1/20 | 0.36 |
| ▸ | LOXL3 | P58215 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10656731 | 0.73 | ABL1 (0.66) | L3MBTL1KDM4EMAPK1ABL1GAA | |
| SCHEMBL972562 | 0.73 | L3MBTL1 (0.43) | L3MBTL1KDM4EMAPK1ABL1GAA | |
| SCHEMBL7719928 | 0.69 | L3MBTL1 (0.40) | L3MBTL1KDM4EMAPK1GAANPC1 | |
| SCHEMBL11050112 | 0.69 | ALDH1A1 (0.46) | L3MBTL1KDM4EMAPK1GAANPC1 | |
| SCHEMBL10656600 | 0.68 | ABL1 (0.58) | L3MBTL1KDM4EMAPK1ABL1GAA | |
| SCHEMBL11059739 | 0.68 | ABL1 (0.49) | L3MBTL1KDM4EMAPK1ABL1GAA | |
| SCHEMBL11091577 | 0.67 | ABL1 (0.42) | L3MBTL1KDM4EMAPK1ABL1GAA | |
| SCHEMBL22331106 | 0.62 | L3MBTL1 (0.42) | L3MBTL1KDM4EMAPK1GAANPC1 | |
| SCHEMBL11013834 | 0.61 | KDM4E (0.34) | L3MBTL1KDM4EMAPK1GAANPC1 | |
| SCHEMBL27543838 | 0.60 | L3MBTL1 (0.41) | L3MBTL1KDM4EMAPK1GAANPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4556671-A | Pharmaceutical formulations | BURROUGHS WELLCOME CO. (US) | 1985-12-03 | — | — | US | disclosed |
| EP-0022578-A1 | Pharmaceutical compositions containing 3-Amino-pyrazoline derivatives | THE WELLCOME FOUNDATION LIMITED (GB) | 1981-01-21 | — | — | EP | disclosed |