Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE3B | Q13370 | 1/20 | 0.62 |
| ▸ | PDE3A | Q14432 | 1/20 | 0.62 |
| ▸ | MAOB | P27338 | 16/20 | 0.48 |
| ▸ | ADH5 | P11766 | 1/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.45 |
| ▸ | MGAM | O43451 | 1/20 | 0.44 |
| ▸ | GAA | P10253 | 1/20 | 0.44 |
| ▸ | SI | P14410 | 1/20 | 0.44 |
| ▸ | MGAM2 | Q2M2H8 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7280962 | 0.77 | PDE3B (1.00) | PDE3BPDE3AADH5ALDH1A1MGAM | |
| SCHEMBL10960764 | 0.76 | MAOB (0.49) | PDE3BPDE3AMAOB | |
| SCHEMBL10620570 | 0.75 | PDE3B (0.63) | PDE3BPDE3A | |
| SCHEMBL7321194 | 0.75 | MAOB (0.53) | MAOB | |
| SCHEMBL10961621 | 0.74 | PDE3B (0.61) | PDE3BPDE3AMAOBADH5 | |
| SCHEMBL10965099 | 0.74 | PDE2A (0.65) | PDE3BPDE3AMAOB | |
| SCHEMBL10962496 | 0.73 | PDE2A (0.64) | PDE3BPDE3AMAOBALDH1A1MGAM | |
| SCHEMBL30305324 | 0.72 | ADH5 (0.66) | PDE3BPDE3AMAOBADH5ALDH1A1 | |
| SCHEMBL10963015 | 0.72 | PDE3B (0.66) | PDE3BPDE3AMAOB | |
| SCHEMBL10511735 | 0.72 | MAOB (0.50) | PDE3BPDE3AMAOB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0149543-A1 | Cardiotonic and antihypertensive oxadiazinone compounds | WARNER-LAMBERT COMPANY (US) | 1985-07-24 | — | — | EP | claimed |
| US-4508718-A | Cardiotonic and antihypertensive oxadiazinone compounds | WARNER-LAMBERT COMPANY (US) | 1985-04-02 | — | — | US | claimed |
| EP-0149543-A1 | Cardiotonic and antihypertensive oxadiazinone compounds | WARNER-LAMBERT COMPANY (US) | 1985-07-24 | — | — | EP | disclosed |
| US-4508718-A | Cardiotonic and antihypertensive oxadiazinone compounds | WARNER-LAMBERT COMPANY (US) | 1985-04-02 | — | — | US | disclosed |