Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CASP6 | P55212 | 2/20 | 0.60 |
| ▸ | NPC1 | O15118 | 1/20 | 0.51 |
| ▸ | CA1 | P00915 | 6/20 | 0.48 |
| ▸ | CA2 | P00918 | 6/20 | 0.48 |
| ▸ | CA9 | Q16790 | 5/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.44 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.44 |
| ▸ | CYP2C19 | P33261 | 3/20 | 0.44 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 1/20 | 0.43 |
| ▸ | HPGD | P15428 | 1/20 | 0.43 |
| ▸ | PHLPP2 | Q6ZVD8 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.43 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.41 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.41 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.41 |
| ▸ | SENP3 | Q9H4L4 | 3/20 | 0.41 |
| ▸ | SENP2 | Q9HC62 | 3/20 | 0.41 |
| ▸ | SENP1 | Q9P0U3 | 3/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8592778 | 0.94 | CASP6 (0.60) | CASP6NPC1CA1CA2CA9 | |
| SCHEMBL8592933 | 0.83 | NPC1 (0.70) | CASP6NPC1CA1CA2CA9 | |
| SCHEMBL3301802 | 0.81 | CASP6 (0.66) | CASP6NPC1CA1CA2CA9 | |
| SCHEMBL6051371 | 0.79 | ALDH1A1 (0.59) | CASP6CA1CA2ALDH1A1HSD17B10 | |
| SCHEMBL11355099 | 0.78 | NPC1 (0.48) | CASP6NPC1CA1CA2CA9 | |
| SCHEMBL10957888 | 0.77 | MAPT (0.56) | CASP6NPC1CA1CA2CA9 | |
| SCHEMBL11813062 | 0.77 | CASP6 (0.53) | CASP6NPC1CA1CA2CA9 | |
| SCHEMBL7225514 | 0.75 | CASP6 (1.00) | CASP6CA1CA2CA9ALDH1A1 | |
| SCHEMBL4102145 | 0.75 | CASP6 (0.79) | CASP6CA1CA2CA9ALDH1A1 | |
| SCHEMBL12555528 | 0.75 | CASP6 (0.57) | CASP6NPC1CA1CA2CA9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4540776-A | Reactive fluorotriazinylaminonaphthotriazolyphenylazopyridone or pyrimidone dyestuffs | BAYER AKTIENGESELLSCHAFT (DE) | 1985-09-10 | — | — | US | disclosed |
| US-4354968-A | Azo reactive dyestuffs having an aryl-triazinyl-aryl diazo component | BAYER AKTIENGESELLSCHAFT (DE) | 1982-10-19 | — | — | US | disclosed |
| US-4118384-A | DIAZOTIZATION | BAYER AKTIENGESELLSCHAFT (DE) | 1978-10-03 | — | — | US | disclosed |
| US-4035350-A | Process for the preparation of water-soluble azo dyestuffs by reacting an aromatic amine and a coupling component with alkali metal nitrite or alkyl nitrite in the absence of acid | HOECHST AKTIENGESELLSCHAFT (DT) | 1977-07-12 | — | — | US | disclosed |