Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CASP6 | P55212 | 1/20 | 0.66 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.47 |
| ▸ | CA2 | P00918 | 6/20 | 0.46 |
| ▸ | CA1 | P00915 | 5/20 | 0.46 |
| ▸ | CA9 | Q16790 | 4/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.44 |
| ▸ | MAPT | P10636 | 2/20 | 0.44 |
| ▸ | HPGD | P15428 | 1/20 | 0.44 |
| ▸ | TIMP3 | P35625 | 3/20 | 0.43 |
| ▸ | NPC1 | O15118 | 1/20 | 0.43 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.42 |
| ▸ | CA3 | P07451 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 2/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.41 |
| ▸ | USP2 | O75604 | 1/20 | 0.41 |
| ▸ | RECQL | P46063 | 1/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8592778 | 0.84 | CASP6 (0.60) | CASP6KMT2ACA2CA1CA9 | |
| SCHEMBL8592935 | 0.83 | CASP6 (0.61) | CASP6KMT2ACA2CA1CA9 | |
| SCHEMBL10897127 | 0.82 | TIMP3 (0.51) | CASP6KMT2AALDH1A1MAPTTIMP3 | |
| SCHEMBL942276 | 0.82 | CASP6 (0.51) | CASP6KMT2ACA2CA1CA9 | |
| SCHEMBL27435997 | 0.81 | ALDH1A1 (0.42) | CASP6KMT2AALDH1A1HPGDTIMP3 | |
| SCHEMBL1857055 | 0.81 | KMT2A (0.59) | CASP6KMT2AALDH1A1KDM4EMAPT | |
| SCHEMBL345331 | 0.81 | CASP6 (0.57) | CASP6KMT2ACA2CA1CA9 | |
| SCHEMBL10960119 | 0.81 | CASP6 (0.60) | CASP6KMT2ACA2CA1CA9 | |
| SCHEMBL10650573 | 0.80 | ALDH1A1 (0.45) | CASP6KMT2ACA2CA1CA9 | |
| SCHEMBL4115318 | 0.80 | KMT2A (0.57) | CASP6KMT2AALDH1A1KDM4EMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 15 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8758501-B2 | Nanoparticulate UV protectant with silicon dioxide coating | MERCK PATENT GMBH (DE) | 2014-06-24 | — | — | US | disclosed |
| US-20100278882-A1 | USE OF PROTEIN MICROBEADS IN COSMETICS | BASF SE (DE) | 2010-11-04 | — | — | US | disclosed |
| US-7820150-B2 | Cosmetic or dermatological formulations of improved pearlescence | BEIERSDORF AG (DE) | 2010-10-26 | — | — | US | disclosed |
| US-20100093984-A1 | EXTRACTION METHOD | WIRTH CORINNA | 2010-04-15 | — | — | US | disclosed |
| US-20100015070-A1 | USE OF NATURAL, RECOMBINANT AND SYNTHETIC RESILINS IN COSMETICS | BASF SE (DE) | 2010-01-21 | — | — | US | disclosed |
| US-20090220441-A1 | Nanoparticulate UV Protectant With Silicon Dioxide Coating | PFLUECKER FRANK | 2009-09-03 | — | — | US | disclosed |
| US-20090098076-A1 | Method For the Production of a Keratin-Binding Effector Molecule | BASF SE (DE) | 2009-04-16 | — | — | US | disclosed |
| US-20090035238-A1 | UV FILTER CAPSULE CONTAINING AN AMINO-SUBSTITUTED HYDROXYBENZOPHENONE | MERCK PATENT GMBH (DE) | 2009-02-05 | — | — | US | disclosed |
| US-20080261844-A1 | Multicolor Cosmetics | BEIERSDORF AG (DE) | 2008-10-23 | — | — | US | disclosed |
| US-20080193569-A1 | Extraction Method for Producing Plant Extracts, Especially Waltheria Paniculata Extracts Containing Tiliroside | MERCK PATENT GESELLSCHAFT (DE) | 2008-08-14 | — | — | US | disclosed |
| US-7264670-B2 | Coloured microstructured effect pigments | MERCK PATENT GESELLSCHAFT (DE) | 2007-09-04 | — | — | US | disclosed |
| US-20060194057-A1 | Silicon dioxide-coated nanoparticulate uv protectant | MERCK PATENT GMBH (DE) | 2006-08-31 | — | — | US | disclosed |
| US-20060039937-A1 | Composition having antioxidant properties | MERCK PATENT GMBH (DE) | 2006-02-23 | — | — | US | disclosed |
| US-20060002875-A1 | Diffractive colorants for cosmetics | MERCK PATENT GMBH (DE) | 2006-01-05 | — | — | US | disclosed |
| US-20050120917-A1 | Coloured microstructured effect pigments | MERCK PATENT GMBH (DE) | 2005-06-09 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (8 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090220441-A1 | Nanoparticulate UV Protectant With Silicon Dioxide Coating | CUTA, SUCLG1, TYR | CASP6 1074/4885KMT2A 3479/4885CA2 2060/4885 |
| US-20060039937-A1 | Composition having antioxidant properties | GPX4, GPX1, CAT | CASP6 559/4885KMT2A 3220/4885CA2 1013/4885 |
| US-20060002875-A1 | Diffractive colorants for cosmetics | RARA, RARG, DSG1 | CASP6 4663/4885KMT2A 1835/4885CA2 3785/4885 |
| US-20090035238-A1 | UV FILTER CAPSULE CONTAINING AN AMINO-SUBSTITUTED HYDROXYBENZOPHENONE | TYR, MITF, UROD | CASP6 2194/4885KMT2A 1604/4885CA2 4665/4885 |
| US-20080193569-A1 | Extraction Method for Producing Plant Extracts, Especially Waltheria Paniculata Extracts Containing Tiliroside | MITF, FZD7, LSS | CASP6 3533/4885KMT2A 2475/4885CA2 3459/4885 |
| US-20100093984-A1 | EXTRACTION METHOD | LSS, TREH, STS | CASP6 1428/4885KMT2A 3123/4885CA2 3220/4885 |
| US-20080261844-A1 | Multicolor Cosmetics | CUTA, TYR, LBR | CASP6 4630/4885KMT2A 2242/4885CA2 1485/4885 |
| US-20090098076-A1 | Method For the Production of a Keratin-Binding Effector Molecule | KRT18, KRTCAP2, CUTA | CASP6 1371/4885KMT2A 2264/4885CA2 2206/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.