Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CISD1 | Q9NZ45 | 2/20 | 0.50 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.39 |
| ▸ | PDE3A | Q14432 | 1/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.38 |
| ▸ | PKM | P14618 | 1/20 | 0.35 |
| ▸ | ATM | Q13315 | 1/20 | 0.35 |
| ▸ | POLB | P06746 | 1/20 | 0.35 |
| ▸ | MEN1 | O00255 | 3/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.35 |
| ▸ | USP2 | O75604 | 2/20 | 0.35 |
| ▸ | LMNA | P02545 | 2/20 | 0.35 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.35 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.35 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.35 |
| ▸ | CLK4 | Q9HAZ1 | 2/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.35 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.35 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.35 |
| ▸ | TSHR | P16473 | 1/20 | 0.35 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10963109 | 0.86 | CISD1 (0.68) | CISD1PDE4DPDE3APKMPOLB | |
| SCHEMBL10963452 | 0.86 | CISD1 (0.47) | CISD1KDM4ELMNAHSD17B10CLK4 | |
| SCHEMBL11231644 | 0.84 | CISD1 (0.52) | CISD1PDE4DPDE3AKDM4EPKM | |
| SCHEMBL10962587 | 0.83 | ALDH1A1 (0.50) | CISD1KDM4EPKMLMNAHSD17B10 | |
| SCHEMBL11223169 | 0.81 | CISD1 (0.46) | CISD1PDE4DPDE3AKDM4EPKM | |
| SCHEMBL2873972 | 0.79 | CISD1 (0.69) | CISD1PDE4DPDE3AKDM4EATM | |
| SCHEMBL11075640 | 0.78 | ALDH1A1 (0.33) | CISD1KDM4ELMNAALDH1A1PTGS2 | |
| SCHEMBL11111306 | 0.77 | PDE4D (0.44) | CISD1PDE4DPDE3AKDM4EPKM | |
| Sulfuric Acid SCHEMBL11159036 | 0.77 | CISD1 (0.45) | CISD1PDE4DPDE3AKDM4EPKM | |
| SCHEMBL10962539 | 0.71 | CISD1 (0.66) | CISD1KDM4EMEN1KMT2AHSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0056970-B1 | ANTHRANILIC ACIDS SUBSTITUTED BY BASIC GROUPS, PROCESS FOR THEIR PREPARATION AND THEIR USE | HOECHST AKTIENGESELLSCHAFT (DE) | 1985-03-27 | — | — | EP | disclosed |
| US-4478843-A | 5-Phenyltetrazoles and their use as salidiuretics | HOECHST AKTIENGESELLSCHAFT (DE) | 1984-10-23 | — | — | US | disclosed |
| EP-0051816-B1 | 5-PHENYLTETRAZOLES SUBSTITUTED BY BASIC GROUPS, METHOD FOR THEIR PREPARATION AND THEIR USE AS DRUGS | HOECHST AKTIENGESELLSCHAFT (DE) | 1984-05-02 | — | — | EP | disclosed |
| US-4406895-A | Base-substituted anthranilic acids, a process for their preparation and their use | HOECHST AKTIENGESELLSCHAFT (DE) | 1983-09-27 | — | — | US | disclosed |
| EP-0056970-A1 | Anthranilic acids substituted by basic groups, process for their preparation and their use | HOECHST AKTIENGESELLSCHAFT (DE) | 1982-08-04 | — | — | EP | disclosed |
| EP-0051816-A1 | 5-Phenyltetrazoles substituted by basic groups, method for their preparation and their use as drugs | HOECHST AKTIENGESELLSCHAFT (DE) | 1982-05-19 | — | — | EP | disclosed |