Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CISD1 | Q9NZ45 | 1/20 | 0.46 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.38 |
| ▸ | PDE3A | Q14432 | 1/20 | 0.38 |
| ▸ | PKM | P14618 | 1/20 | 0.34 |
| ▸ | POLB | P06746 | 2/20 | 0.34 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.33 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.33 |
| ▸ | TSHR | P16473 | 2/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | USP2 | O75604 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.33 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.33 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.33 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.33 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.33 |
| ▸ | CLK4 | Q9HAZ1 | 1/20 | 0.33 |
| ▸ | CA1 | P00915 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11231644 | 0.87 | CISD1 (0.52) | CISD1PDE4DPDE3APKMPOLB | |
| SCHEMBL10965554 | 0.83 | ALDH1A1 (0.46) | CISD1PKMPOLBALDH1A1TDP1 | |
| SCHEMBL10963109 | 0.83 | CISD1 (0.68) | CISD1PDE4DPDE3APKMPOLB | |
| SCHEMBL11555157 | 0.82 | CISD1 (0.48) | CISD1PDE4DPDE3APOLBPTGS2 | |
| SCHEMBL10962960 | 0.81 | CISD1 (0.50) | CISD1PDE4DPDE3APKMPOLB | |
| SCHEMBL11111306 | 0.77 | PDE4D (0.44) | CISD1PDE4DPDE3APKMPOLB | |
| SCHEMBL11098356 | 0.77 | CISD1 (0.43) | CISD1PDE4DPDE3APOLBPTGS2 | |
| SCHEMBL11215820 | 0.76 | CISD1 (0.43) | CISD1PDE4DPDE3APOLBPTGS2 | |
| Sulfuric Acid SCHEMBL11159036 | 0.75 | CISD1 (0.45) | CISD1PDE4DPDE3APKMPOLB | |
| SCHEMBL11219712 | 0.74 | ALPL (0.37) | CISD1ALDH1A1TDP1LMNACA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4341773-A | 2,4-Diamino-5-sulfamoylbenzene sulfonic acids and process for their manufacture | HOECHST AKTIENGESELLSCHAFT (DE) | 1982-07-27 | — | — | US | disclosed |