Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.33 |
| ▸ | HTT | P42858 | 1/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | LRRK2 | Q5S007 | 1/20 | 0.32 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.31 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.31 |
| ▸ | LMNA | P02545 | 1/20 | 0.31 |
| ▸ | HPGD | P15428 | 1/20 | 0.31 |
| ▸ | CISD1 | Q9NZ45 | 1/20 | 0.30 |
| ▸ | CA2 | P00918 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10962960 | 0.78 | CISD1 (0.50) | ALDH1A1KDM4EPTGS1PTGS2LMNA | |
| SCHEMBL10963452 | 0.72 | CISD1 (0.47) | ALDH1A1HTTKDM4ELRRK2LMNA | |
| SCHEMBL7519732 | 0.70 | TSHR (0.37) | ALDH1A1HTTKDM4ELMNAHPGD | |
| SCHEMBL2779567 | 0.68 | NPC1 (0.38) | ALDH1A1HTTKDM4ELMNAHPGD | |
| SCHEMBL10962587 | 0.68 | ALDH1A1 (0.50) | ALDH1A1KDM4ELMNAHPGDCISD1 | |
| SCHEMBL10963109 | 0.67 | CISD1 (0.68) | ALDH1A1CISD1CA2 | |
| SCHEMBL11231644 | 0.65 | CISD1 (0.52) | ALDH1A1KDM4EPTGS2HPGDCISD1 | |
| SCHEMBL8568767 | 0.62 | HDAC6 (0.45) | ALDH1A1HTTKDM4ELRRK2PTGS1 | |
| SCHEMBL2073157 | 0.61 | KDM4E (0.44) | ALDH1A1HTTKDM4ELMNAHPGD | |
| SCHEMBL1958228 | 0.61 | POLB (0.48) | ALDH1A1HTTKDM4ECA2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4478843-A | 5-Phenyltetrazoles and their use as salidiuretics | HOECHST AKTIENGESELLSCHAFT (DE) | 1984-10-23 | — | — | US | disclosed |
| US-4406895-A | Base-substituted anthranilic acids, a process for their preparation and their use | HOECHST AKTIENGESELLSCHAFT (DE) | 1983-09-27 | — | — | US | disclosed |