Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA1 | P00915 | 3/20 | 0.53 |
| ▸ | CA2 | P00918 | 3/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.50 |
| ▸ | MEN1 | O00255 | 2/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.50 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.50 |
| ▸ | CES1 | P23141 | 2/20 | 0.50 |
| ▸ | CRHBP | P24387 | 1/20 | 0.50 |
| ▸ | ATM | Q13315 | 1/20 | 0.50 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.50 |
| ▸ | TLR9 | Q9NR96 | 1/20 | 0.50 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.48 |
| ▸ | TSHR | P16473 | 2/20 | 0.47 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.47 |
| ▸ | CA12 | O43570 | 1/20 | 0.46 |
| ▸ | CA3 | P07451 | 1/20 | 0.46 |
| ▸ | CA4 | P22748 | 1/20 | 0.46 |
| ▸ | CA6 | P23280 | 1/20 | 0.46 |
| ▸ | CA5A | P35218 | 1/20 | 0.46 |
| ▸ | CA7 | P43166 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29182467 | 0.82 | ALDH1A1 (0.57) | CA1CA2ALDH1A1MEN1KMT2A | |
| SCHEMBL24393521 | 0.80 | ALDH1A1 (0.57) | CA1CA2ALDH1A1MEN1KMT2A | |
| SCHEMBL1177204 | 0.80 | TSHR (0.57) | CA1CA2ALDH1A1MEN1KMT2A | |
| SCHEMBL21247872 | 0.77 | ALDH1A1 (0.67) | CA1CA2ALDH1A1MEN1KMT2A | |
| SCHEMBL11812108 | 0.74 | ALDH1A1 (0.50) | CA1CA2ALDH1A1MEN1KMT2A | |
| SCHEMBL4162102 | 0.74 | TSHR (0.55) | CA1CA2ALDH1A1MEN1KMT2A | |
| SCHEMBL11291473 | 0.74 | ALDH1A1 (0.62) | ALDH1A1MEN1KMT2AL3MBTL1CES1 | |
| SCHEMBL11612271 | 0.74 | ALDH1A1 (0.62) | ALDH1A1MEN1KMT2AL3MBTL1CES1 | |
| SCHEMBL2112582 | 0.74 | ESR1 (0.54) | CA1CA2ALDH1A1MEN1KMT2A | |
| SCHEMBL17766705 | 0.74 | MMP1 (0.47) | CA1CA2ALDH1A1MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0052842-B1 | N,N-DIARYL CARBAMOYL FLUORIDES, PROCESS FOR PREPARING THEM AND THEIR USE IN THE PREPARATION OF UREAS, AND THE UREAS OBTAINED THEREBY | BAYER AG (DE) | 1985-09-18 | — | — | EP | disclosed |
| EP-0052842-A2 | N,N-diaryl carbamoyl fluorides, process for preparing them and their use in the preparation of ureas, and the ureas obtained thereby | BAYER AG (DE) | 1982-06-02 | — | — | EP | disclosed |